Research work by faculty and students in our department has generated nearly 30 manuscript publications.
New publications (June 2025-current):
Synergistic effects of HO-1 inhibition and chemotherapy on tumor proliferation and immune infiltration: An in vitro and in vivo approach to enhancing prostate cancer treatment.
Salloom RJ, Sahtout DZ, Ahmad IM, Abdalla MY. Transl Oncol. 2025 Apr;54:102339. doi: 10.1016/j.tranon.2025.102339. Epub 2025 Mar 3. PMID: 40037158
Molecular Dynamics of Trogocytosis and Other Contact-Dependent Cell Trafficking Mechanisms in Tumor Pathogenesis.
Marcarian HQ, Sivakoses A, Bothwell ALM. Cancers (Basel). 2025 Jul 8;17(14):2268. doi: 10.3390/cancers17142268. PMID: 40723152
Comprehensive characterization of nodal peripheral T-cell lymphoma, not otherwise specified: A report of the 2023 SH/EA4HP lymphoma workshop.
Amador C, Bouska A, Shah R, Iqbal J, Vega F. Am J Clin Pathol. 2025 Jul 11;164(1):65-75. doi: 10.1093/ajcp/aqaf025. PMID: 40646677
Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma.
Bouska A, Zhang W, Sharma S, Holte H, Shah RA, Lone WG, Soma MA, Yang R, Liu X, Mehmood S, Chawla RS, Cappelli LV, Fiore D, Gong Q, Heavican-Foral TB, Cannatella JJ, Amador C, Arif A, Smith LM, Lim ST, Ong CK, Feldman AL, Du MQ, Perry AM, de Leval L, Greiner TC, Fu K, Trøen G, Vodák D, Nakken S, Delabie J, Weinstock D, Pileri S, Laginestra A, Kim K, Pajvani U, Vose JM, Weisenburger DD, Horwitz SM, Dave S, Khoury J, Inghirami G, Chan WC, Iqbal J. Am J Hematol. 2025 Jun 13. doi: 10.1002/ajh.27736. Online ahead of print. PMID: 40510016
Development of a national pathology training system using digital pathology and SNOMED-CT.
McGenity C, Cratchley A, Aldridge J, Sayers C, Campbell WS, Dash RC, Flanagan AM, Sebire N, Wright A, Akhtar W, Treanor D. J Pathol Inform. 2025 Jun 18;18:100456. doi: 10.1016/j.jpi.2025.100456. eCollection 2025 Aug. PMID: 40688393 Free PMC article.
Distal intracranial artery pseudoaneurysm causing subdural hematoma: An illustrative case and a systematic review.
Patel KR, Thorell WE, Borg N, Surdell DL, Tran U, Schmidt CM, Cathcart SJ, Sattur MG. Surg Neurol Int. 2025 Jun 6;16:224. doi: 10.25259/SNI_186_2025. eCollection 2025. PMID: 40656504
Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease.
Chen CD, Franklin EE, Li Y, Joseph-Mathurin N, Burns AL, Hobbs DA, McCullough AA, Schultz SA, Xiong C, Wang G, Masellis M, Hsiung GR, Gauthier S, Berman SB, Roberson ED, Honig LS, Clarnette R, Ringman JM, Galvin JE, Brooks W, Suzuki K, Black S, Levin J, Aggarwal NT, Jucker M, Frosch MP, Kofler JK, White C 3rd, Keene CD, Chen J, Daniels A, Gordon BA, Ibanez L, Karch CM, Llibre-Guerra J, McDade E, Morris JC, Supnet-Bell C, Allegri RF, Lee JH, Day GS, Lopera F, Roh JH, Schofield PR, Mills S, Benzinger TLS, Bateman RJ, Perrin RJ; DIAN-TU Study Team; DIAN-Obs Study Team. Acta Neuropathol. 2025 Jun 3;149(1):57. doi: 10.1007/s00401-025-02890-7. PMID: 40459787
Spinal Metastases from Gastrointestinal Stromal Tumor: A Case Report.
Lookian PP, Weisbrod LJ, Rasmussen JM, Ehlers LD, Chen J, Teichmeier TR, Katzir M. Case Rep Oncol. 2025 May 14;18(1):675-681. doi: 10.1159/000543568. eCollection 2025 Jan-Dec. PMID: 40487557
The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation.
Yamada T, Cohen SM, Lake BG. Crit Rev Toxicol. 2025 Jun 27:1-38. doi: 10.1080/10408444.2025.2513332. Online ahead of print. PMID: 40574714 Free article. Review.
ToxPoint: Chemical risks and children’s health-building on progress based on science, not panic.
Cohen SM, Rietjens IMCM, Levy L; Alliance of Scientists for Evidence-Based Risk Assessment. Toxicol Sci. 2025 Jul 1;206(1):1-3. doi: 10.1093/toxsci/kfaf051. PMID: 40567060 Free PMC article. No abstract available.
An evaluation of the human relevance of the hepatocellular tumors observed in mice treated with synthetic fungicide, pyridachlometyl, based on mode of action.
Kawamoto K, Shimotsuma Y, Maeda K, Matsunaga K, Asano H, Cohen SM, Yamada T. Arch Toxicol. 2025 Jun 9. doi: 10.1007/s00204-025-04099-9. Online ahead of print. PMID: 40488882
FOXM1 targeting alters AURKB activity and reshapes antitumor immunity to curb the progression of small cell lung cancer.
Khan MA, Khan P, Fatima M, Rehman AU, Anwar L, Alsafwani ZW, Ahmad A, Zaidi MAA, Cox JL, Zahid A, Mohiuddin S, Kim SH, Santamaria-Barria JA, Lakshmanan I, Katzenellenbogen BS, Katzenellenbogen JA, Ganti AK, Batra SK, Nasser MW. Res Sq [Preprint]. 2025 Jul 1:rs.3.rs-6960266. doi: 10.21203/rs.3.rs-6960266/v1. PMID: 40630538
Primary Neuroendocrine Tumors of the Genitourinary System: Two Rare Examples of Testicular and Renal Neuroendocrine Tumors with Clinicopathologic and Molecular Findings.
Manzo R, Renavikar PS, Cushman-Vokoun A, Wagner DG, Lele SM. Int J Surg Pathol. 2025 Jul 7:10668969251350265. doi: 10.1177/10668969251350265. Online ahead of print. PMID: 40620063
Histidine decarboxylase inhibition attenuates cancer-associated muscle wasting.
Dasgupta A, Schmitt RE, Kono T, Lee CC, Zoberi MI, Epstein SA, Schneider JZ, Hernandez A, Grandgenett PM, Caffrey TC, DiMaio DJ, Hollingsworth MA, Doles JD. J Exp Med. 2025 Sep 1;222(9):e20242239. doi: 10.1084/jem.20242239. Epub 2025 Jul 2. PMID: 40600951
Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis.
Bhalerao N, Ogoti Y, Peura J, Johnson C, Chen Q, Korobkina ED, Keller FN, Wengyn M, Norgard RJ, Shamber C, Klute K, DiMaio D, Sellin K, Grandgenett PM, Li R, Hollingsworth MA, Guilherme A, Czech MP, Kremer R, Zhu LJ, Watson EV, Ruscetti M, Guertin DA, Pitarresi JR. bioRxiv [Preprint]. 2025 Jun 7:2025.06.03.657464. doi: 10.1101/2025.06.03.657464. PMID: 40501563
Nipah virus: a summary for clinicians.
Levine CB, Sauer LM, McLellan SLF, Evans JD; State of the Science Working Group of the National Ebola Training and Education Center’s (NETEC’s) Special Pathogens Research Network (SPRN). Int J Emerg Med. 2025 Jul 9;18(1):126. doi: 10.1186/s12245-025-00916-1. PMID: 40634915
Effect of aging on the development and progression of alcohol-associated liver disease.
Bellamkonda R, Mahalingam S, Ethiraj O, Perumal SK, Arumugam MK, Knoell DL, Fisher KW, Casey CA, Kharbanda KK, Rasineni K. Alcohol Clin Exp Res (Hoboken). 2025 Jul;49(7):1412-1423. doi: 10.1111/acer.70086. Epub 2025 Jun 3. PMID: 40462406
Refining the adriamycin-induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare.
Jiang H, Althobaiti S, Pinkerton B, Fu X, Jia Z, Foster KW, Thiele GM, Plumb TJ, Wang D. Animal Model Exp Med. 2025 May;8(5):854-863. doi: 10.1002/ame2.12564. Epub 2025 Feb 7. PMID: 39917824
High-grade B-cell lymphoma, not otherwise specified: an LLMPP study.
Collinge BJ, Hilton LK, Wong JCH, Alduaij W, Ben-Neriah S, Slack GW, Farinha P, Boyle M, Meissner B, Cook JR, Ott G, Rosenwald A, Campo E, Amador C, Greiner TC, Raess PW, Song JY, Inghirami GG, Ondrejka SL, Jaffe ES, Weisenburger DD, Chan WC, Holte H, Beiske K, Fu K, Delabie J, Pittaluga S, Iqbal J, Wright G, Savage KJ, Mungall AJ, Staudt LM, Steidl C, Feldman AL, Morin RD, Rimsza LM, Scott DW. Blood Adv. 2025 Jul 17:bloodadvances.2025016651. doi: 10.1182/bloodadvances.2025016651. Online ahead of print. PMID: 40674706
T- and NK-cell lymphomas and leukemias: Insights from the 2023 Society for Hematopathology/European Association for Haematopathology Workshop.
Vega F, Bueso Ramos C, Iqbal J, Medeiros LJ. Am J Clin Pathol. 2025 Jul 11;164(1):4-6. doi: 10.1093/ajcp/aqae168. PMID: 40646673 No abstract available.
AttentionAML: An Attention-based Deep Learning Framework for Accurate Molecular Categorization of Acute Myeloid Leukemia.
Li L, Khoury JD, Wang J, Wan S. bioRxiv [Preprint]. 2025 May 22:2025.05.20.655179. doi: 10.1101/2025.05.20.655179. PMID: 40475602
Immune dysfunction during S. aureus biofilm-associated implant infections: opportunities for novel therapeutic strategies.
Brandquist ND, Kielian T. NPJ Biofilms Microbiomes. 2025 Jul 25;11(1):144. doi: 10.1038/s41522-025-00782-y. PMID: 40715142 Free article. Review.
Immunometabolism shapes chronic Staphylococcus aureus infection: insights from biofilm infection models.
Ogunware AE, Kielian T. Curr Opin Microbiol. 2025 Aug;86:102612. doi: 10.1016/j.mib.2025.102612. Epub 2025 May 22. PMID: 40409167
An exciting future for microbial molecular biology and physiology.
Bridges AA, Guthrie L, Lehman M, Kellogg EH, Miranda SW, Pountain A, Shiver AL, Varble A; Molecular Biology and Physiology Community of the Council on Microbial Sciences; Kaplan HB, Shank EA, Storz G. mBio. 2025 Jun 30:e0069425. doi: 10.1128/mbio.00694-25. Online ahead of print. PMID: 40586574
Pre-Treatment Tumor Collagen is Associated with Triple-Negative Breast Cancer Pathological Response to Chemo-Immunotherapy.
Jones M, Alsafwani ZW, Orozco JIJ, Lele SM, Nasser MW, Batra SK, Santamaria-Barria JA. Ann Surg Oncol. 2025 Jul 21. doi: 10.1245/s10434-025-17904-7. Online ahead of print. PMID: 40690171
Thiotepa-Induced Toxicity: A Clinical Mimic of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Featuring Severe Mucositis, Diffuse Dusky Discoloration, and Skin Sloughing.
Shaker N, Phelps R, Niedt G, Ben Musa R, Bhowmik R, Sangueza OP, Pradhan D. Am J Dermatopathol. 2025 Apr 1;47(4):269-273. doi: 10.1097/DAD.0000000000002923. Epub 2025 Feb 6. PMID: 39912674
BRCA1-Associated Protein-1 Inactivated Melanoma Arising in a Pre-existing Nevus With ALK Fusion and Low Tumor Mutational Burden.
Shaker N, Phelps R, Niedt G, Sangueza O, Krishnan R, Patel A, Torres-Cabala C, Aung PP, Prieto V, Dumur CI, Pradhan D. Am J Dermatopathol. 2025 Apr 1;47(4):264-268. doi: 10.1097/DAD.0000000000002925. Epub 2025 Feb 6. PMID: 39912664
ST6GalNAc-I regulates tumor cell sialylation via NECTIN2/MUC5AC-mediated immunosuppression and angiogenesis in non-small cell lung cancer.
Appadurai MI, Chaudhary S, Shah A, Natarajan G, Alsafwani ZW, Khan P, Shinde DD, Lele SM, Smith LM, Nasser MW, Batra SK, Ganti AK, Lakshmanan I. J Clin Invest. 2025 May 15;135(10):e186863. doi: 10.1172/JCI186863. eCollection 2025 May 15. PMID: 40371640