Department researchers have been awarded one grant. In addition, our researchers’ work has generated 33 manuscript publications.
New grant:
PI: Xian Jie
Funder: NIGMS R35
Title: Biological roles and mechanisms of cell surface RNAs in human papillomavirus endocytic trafficking
Amount: $275,000 (direct cost)
4/5/26-2/28/27
New publications (April 2026-current):
Dietary Fat Content Influences PanIN Progression and Pancreatic Cancer Development in Mice.
Sardarni UK, Faraoni EY, Waller AM, Strickland LN, O’Brien B, Klute KA, Cox JL, McAllister F, Bailey-Lundberg JM. Cancer Res Commun. 2026 May 1;6(5):1036-1047. doi: 10.1158/2767-9764.CRC-25-0777. PMID: 42001482
An anti-adhesive compound modulating the production of Staphylococcus aureus cell wall-anchored proteins.
Leonard AC, Bao R, Menjivar C, Myers MJ, Paiva TO, Zheng Z, Berry KA, Bayles KW, Flannagan RS, Dufrêne YF, Bose JL, Heinrichs DE, Cox G. Nat Commun. 2026 Apr 15. doi: 10.1038/s41467-026-71917-8. Online ahead of print. PMID: 41986312
Platelet storage lesion underlies changes in plasminogen activator inhibitor-1 activity in stored whole blood.
Maginot ER, Barmettler NK, Gawargi FI, Moore EE, White CM, Hiser DC, Clegg AA, Sextro KS, Moody TB, Volk GE, Moore HB, Goodman N, Bobr A, Henry R, Barrett CD; Omaha, Nebraska. J Trauma Acute Care Surg. 2026 Apr 23. doi: 10.1097/TA.0000000000005012. Online ahead of print. PMID: 42023949
Tet2 deficiency alters CD4+ T cell function and promotes T cell lymphoma with a TFH cell immunophenotype.
Heavican-Foral TB, Li Y, Lone W, Bouska A, Zhang J, Yang R, Liu X, Shah AR, Mir AR, Rohr J, Jochum D, Kumar A, Chawla RS, Amador C, Yu J, Herek T, Robinson J, Bi C, Sharma S, Gilbreath T, Hyde RK, McKeithan TW, Lio CW, Rao A, Inghirami G, Khoury J, Chan WC, Iqbal J. J Exp Med. 2026 Jun 1;223(6):e20250194. doi: 10.1084/jem.20250194. Epub 2026 Apr 28. PMID: 42047684
Real-time diagnosis of adult T-cell leukemia/lymphoma using HBZ RNA in situ hybridization.
Amador C, Poveda JC, Mohammed I, Bouska A, Hyjek E, Gibson S, Horna P, Rech KL, Ramos JC, Delma KS, Koepplin JW, Moscinski LC, Cassidy DP, Dicaudo DJ, Sokol L, Iqbal J, Chapman JR. Am J Clin Pathol. 2026 May 5;165(5):aqag030. doi: 10.1093/ajcp/aqag030. PMID: 42106909
Factors affecting detection and quantification of Schistosoma haematobium eggs in pooled urine samples.
Degarege A, Levecke B, Bilder CR, Brett-Major DM, Animut A, Negash Y, Broadhurst MJ, Michaud TL, Erko B. PLoS Negl Trop Dis. 2026 Jun 1;20(6):e0014407. doi: 10.1371/journal.pntd.0014407. eCollection 2026 Jun. PMID: 42224359
Dynamic changes in cuticular chitin enhance mechanical resilience of the tick alloscutum during engorgement.
Garman C, Armendariz S, Peklo MM, Aden SS, Kozisek F, Qian W, Muthukrishnan S, Thomas VC, Turner JA, Chaudhari SS. Insect Biochem Mol Biol. 2026 Jun;191:104567. doi: 10.1016/j.ibmb.2026.104567. Epub 2026 Apr 22. PMID: 4203107
Intracranial mesenchymal tumor, FET::CREB fusion-positive: An integrative analysis of 81 cases.
Rajan S, Chung HJ, Wu Z, Singh O, Dazelle K, Abdullaev Z, Tyagi M, Ferrone CK, Raffeld M, Lee I, Gagan J, Chen J, Cathcart S, Giannini C, Nguyen A, Gokden M, Perry A, Fernandes IL, Putnam AR, Kurek K, Green RM, Eberhart C, Lucas CH, Gonzalez-Gomez I, Lopez GY, Jones K, Prayson R, Yeaney G, Dermawan JKT, Chkheidze R, Appin C, Uhlmann EJ, Taliansky A, Blessing M, Mohila C, Cotter J, Deisch J, Andreiuolo F, Crawford JR, Mount C, Stemmer-Rachamimov AO, Lakis NS, Schmidt R, Chacko G, Newbury R, Neill S, Morales B, Fecher R, Sloan EA, Solomon DA, Nasrallah M, Quezado M, Fonseca A, Aldape K. Neuro Oncol. 2026 Apr 1;28(4):939-951. doi: 10.1093/neuonc/noag001. PMID: 41569358
Response to Mr. DiNardo’s “Letter to the Editor: Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products”.
Norman KG, Kaufman LE, Griem P, D’Ruiz C, Loretz L, Kowcz A, Cohen SM, Scialli AR, Boobis AR, Jacobson-Kram D, Schoeny R, Rosol TJ, Williams GM, Kaminski NE, Guengerich FP, Nash JF. Crit Rev Toxicol. 2026;56(3):231-233. doi: 10.1080/10408444.2026.2640896. Epub 2026 Apr 13. PMID: 41973226
Sex- and Age-Dependent Neuroimmune Dysregulation and Early Neurodegenerative Signatures Following SARS-CoV-2 Infection in Golden Syrian Hamsters.
Kumar N, Acharya A, Das R, Sardarni UK, Tayo OI, Murakonda SP, Sutar D, Venkatesan A, Ampasala DR, Cohen SM, Samuelson MM, Sajja BR, Dettmer U, Ramalingam N, Chand HS, Byrareddy SN. Res Sq [Preprint]. 2026 Apr 7:rs.3.rs-9130692. doi: 10.21203/rs.3.rs-9130692/v1. PMID: 41994117
The use of cultured human hepatocytes as a test system to evaluate cell proliferation as a key event in nongenotoxic carcinogenesis.
Cowie DE, Cohen SM, Goettel M, Lake BG, Nadzialek S, Rooni U, Schutte ME, Tinwell H, Turiccki J, Yamada T, Strupp C. Arch Toxicol. 2026 May 5. doi: 10.1007/s00204-026-04411-1. Online ahead of print. PMID: 42086803
Targeting Oncomucin-driven Immunosuppression Improves the Efficacy of K-rasG12D Inhibition in Pancreatic Cancer.
Bhyravbhatla N, Alsafwani ZW, Thapa I, Nallasamy P, Atri P, Moran Segura CM, Park MA, Khan I, Villalobos-Ayala K, Marimuthu S, Cox JL, Centeno BA, Aithal A, Malafa M, Ghersi D, Batra SK, Kumar S. Gastroenterology. 2026 May 25:S0016-5085(26)06878-2. doi: 10.1053/j.gastro.2026.04.041. Online ahead of print. PMID: 42191046
SLC22A3/OCT3 drives serotonin-mediated stemness in pancreatic cancer.
Krishna Kumar N, Varadharaj V, Gayen N, Kaur AB, Arikath K, Shah A, Mathivanan P, Nallasamy P, Alsafwani ZW, Seshadri B, Raut P, Rauth S, Persinger J, Brahma S, Schott M, Oberley-Deegan RE, Talmon GA, Cox JL, Batra SK, Ponnusamy MP. Cell Rep. 2026 Jun 5;45(6):117387. doi: 10.1016/j.celrep.2026.117387. Online ahead of print. PMID: 42250222
Primary Cutaneous Gamma-Delta T-Cell Lymphoma With Aberrant CD20 Expression: Answer.
Ahmed AA, Khoury JD, Desai KR, Pradhan D. Am J Dermatopathol. 2026 May 1;48(5):404-405. doi: 10.1097/DAD.0000000000003245. PMID: 42012244
Rapidly Enlarging Indurated and Ulcerated Nodules in an Elderly Woman.
Ahmed AA, Khoury JD, Desai KR, Pradhan D. Am J Dermatopathol. 2026 May 1;48(5):e38-e39. doi: 10.1097/DAD.0000000000003244. PMID: 42012249
Two case reports on the identification and management of hypervirulent Klebsiella pneumoniae isolated in Nebraska, USA.
Stevenson JS, Dyer ED, Fey PD, Van Schooneveld TC, Wiley MR, Iwen PC, Carlino-MacDonald U, Russo TA. ASM Case Rep. 2026 Mar 11;2(3):e00233-25. doi: 10.1128/asmcr.00233-25. eCollection 2026 May. PMID: 42094992
Prolonged Cold Ischemic Time Before Normothermic Machine Perfusion Accentuates Postreperfusion Hepatocellular Injury.
Merani S, Scheele K, Fristoe L, Cloonan M, Uhm S, Urban M, Fisher KW, Langnas AN, Andrews MT. Transplant Direct. 2026 Apr 21;12(5):e1943. doi: 10.1097/TXD.0000000000001943. eCollection 2026 May. PMID: 42027371
Hepatocyte-Specific Deletion of Betaine-Homocysteine Methyltransferase Disrupts Methionine Metabolism and Promotes the Spontaneous Development of Hepatic Steatosis.
Rajamanickam R, Perumal SK, Bellamkonda R, Mahalingam S, Fisher KW, Quadros R, Gurumurthy CB, Arumugam MK, Rasineni K, Kharbanda KK. Biomolecules. 2026 Apr 20;16(4):606. doi: 10.3390/biom16040606. PMID: 42072727
EBV-positive CD8 + peripheral T-cell lymphoma in the post-transplant setting: case report and review of the literature.
Ahmed AA, Zhang S, Ronaghy A, Hafeez S, Pradhan D, Gupta N. J Hematop. 2026 Apr 13;19(1):15. doi: 10.1007/s12308-026-00694-6. PMID: 41975104
Emergence of Extensively Drug-Resistant Shigellosis – United States, 2011-2023.
Logan N, Birhane MG, McDonald SL, Alarcón J, Amador S, Anand M, Bachmann LH, Bernard K, Black LS, Chen AN, Cooley LA, Fortes ED, Gerard M, Jervis RH, Kimura AC, Lamba K, Latash J, Li L, Pederson G, Kauffman CP, Reynolds JL, Santiago R Jr, Siemetzki-Kapoor U, Smole SC, Tagg KA, Vostok J, Webb HE, Francois Watkins LK; XDR Shigella Working Group. MMWR Morb Mortal Wkly Rep. 2026 Apr 9;75(13):173-178. doi: 10.15585/mmwr.mm7513a1. PMID: 41955161
- XDR Shigella Working Group:
Shana M Altman 1 , Kyli Beaulieu 2 , Oliver M Beaumont 3 , Raychel Berkheimer 4 , Brianna Loeck 5 , Sean C Buuck 6 , Lisandra Clarke 7 , Matthew Collins 8 , Irina Cody 9 , Stephen Combes 10 , MaryBeth DeMarco 11 , Sarah Feeney 8 , Michael Gosciminski 12 , Samir Hanna 13 , Noël V Hatley 14 , Peter C Iwen 15 , Jennifer A Khoury 16 , Lauren Kleamenakis 4 , Julia Maeda 3 , Jack Marr 17 , Naiyma Martin 18 , Nkuchia M M’ikanatha 19 , Nancy Persson 12 , Craig Rothfuss 20 , Carrell T Rush 16 , Sameera Sayeed 19 , Sarah Shrum Davis 18 , Shamika Smith 21 , Laurie K Stewart 14 , Quoc Phung Than 9 , Rosalie T Trevejo 22 , Christina L Turner 23 , Elena Washington 23 , Sophia Wozny 24 , Mary Whisnant 25 , Michelle Yang 25
Genetic Profile, Treatment Response, and Outcomes of BCR::ABL1-Positive Mixed-Phenotype Acute Leukemia: A Study from the BCR::ABL1 Pathology Group.
Shen Q, Huang X, Wang X, Shuai W, Fang H, Jabbour E, Chen W, Tashakori M, Khanlari M, Wu X, Shao L, Zhang L, El Hussein S, Konoplev S, Khoury JD, Tang G, Wang W, Wang SA, Medeiros LJ, Hu S. Mod Pathol. 2026 May 21:101016. doi: 10.1016/j.modpat.2026.101016. Online ahead of print. PMID: 42173285
Practical approaches to the diagnosis and differential diagnosis of T-lymphoblastic leukemia/lymphoma.
Wang WJ, Khoury JD, Fang H, Medeiros LJ, Wang W. Hum Pathol. 2026 Jun 4:106198. doi: 10.1016/j.humpath.2026.106198. Online ahead of print. PMID: 42248336
Unintended consequences of legacy oversight in digital medicine.
Lennerz JK, Allende D, Aron M, Eltoum IE, Fadare O, Findeis-Hosey J, Gonzalez-Cuyar LF, Hameed M, Khanafshar E, Lazenby AJ, Montone KT, Pantanowitz L, Reid MD, Suarez A, Warrick J, Whitney-Miller CL, Staats PN, Bracamonte ER, Stowman AM. Nat Med. 2026 May 20. doi: 10.1038/s41591-026-04417-3. Online ahead of print. PMID: 42162370
Idiopathic granulomatous mastitis as an autoimmune disease: A review of immunopathogenesis and therapeutic response.
Bergstrom LK, Jaen DM, Lamelas A, Helseth KA, Harwell PA, Millen JC, Renavikar PS, Lele SM, Arthur MR, Lonowski SL, Thiele GM, Mitchell KB, Saunders TE, Stone K, Yang R, Hong J, Medlin JL, Santamaria-Barria JA. Autoimmun Rev. 2026 May 22;25(7):104082. doi: 10.1016/j.autrev.2026.104082. Online ahead of print. PMID: 42173230
CRISPRi and beyond: studying essential gene function in the obligate intracellular bacterium Chlamydia trachomatis.
Gopinath A, Shen L, Ouellette SP. J Bacteriol. 2026 May 21;208(5):e0005926. doi: 10.1128/jb.00059-26. Epub 2026 Apr 22. PMID: 42017790
Water-soluble swab material for environmental sampling.
Crown KK, Lambert TN, Kelly M, Bell NS, Santarpia J. Appl Environ Microbiol. 2026 May 20;92(5):e0003026. doi: 10.1128/aem.00030-26. Epub 2026 Apr 29. PMID: 42053317
Spermidine biosynthesis by hypervirulent Francisella tularensis promotes fitness and salvages adenine.
Yue Y, Shinde D, Moore R 2nd, Yu Y, Thomas VC, Helikar T, Larson MA. J Bacteriol. 2026 May 21;208(5):e0061625. doi: 10.1128/jb.00616-25. Epub 2026 Apr 22. PMID: 42017657
AI-powered Deep Visual Proteomics reveals critical molecular transitions in pancreatic cancer precursors.
Min J, Schweizer L, Zonderland G, Chellakkan Selvanesan B, Thomsen JH, Oldenburg L, Bae SW, Kim B, Hernandez SD, Jez G, Bernard V, Swanson BJ, Klute KA, Wang H, Caffrey TC, Grandgenett PM, Hollingsworth MA, Ummat I, Strauss MT, Mund A, Maitra A. Cancer Discov. 2026 Apr 21. doi: 10.1158/2159-8290.CD-25-1119. Online ahead of print. PMID: 42013410
Instability in Pentanucleotide Markers in a Subset of Microsatellite Instability-High Colorectal Cancer.
Yilmaz A, Frankel WL, Swanson BJ, Miller K, Bacher J, Bigley C, Nelsen L, Kalady MF, Coleman JF, Pearlman R, Hampel H. Curr Oncol. 2026 Apr 2;33(4):205. doi: 10.3390/curroncol33040205. PMID: 42041724
Classic Hodgkin lymphoma with IGH::CCND1 rearrangement: evidence of clonal relation to preceding mantle cell lymphoma.
Ahmed AA, Tadros S. Blood. 2026 May 7;147(19):2278. doi: 10.1182/blood.2025032107. PMID: 42096246
Antagonism of RNA silencing in the yellow fever mosquito, Aedes aegypti, by the nsP2 protein of the prototype alphavirus.
Gupta AK, Wiley MR, Myles KM. Proc Natl Acad Sci U S A. 2026 Feb 17;123(7):e2521417123. doi: 10.1073/pnas.2521417123. Epub 2026 Feb 9. PMID: 41662525
Two Coding-Complete Genomes of Tick-Borne Encephalitis Virus Sequenced from Ixodes persulcatus Collected in Bulgan, Mongolia.
Cleary NG, Tsevelmaa N, Paoli JE, Hoylman M, Altantogtokh D, Wiley MR, Wiley JD, Perez Jimenez JG, Salyer A, Etobayeva IV, Davaasuren N, Bolorchimeg B, Amgalanbayar B, Mavian C, Letizia AG, Boldbaatar B, von Fricken ME. Pathogens. 2026 Apr 1;15(4):378. doi: 10.3390/pathogens15040378. PMID: 42075705
Leukapheresis in Pediatric T-ALL with Extreme Hyperleukocytosis: A Case Highlighting the Importance of Early Recognition.
Guild A, Salomon J, Thakker J, Williams SM, Ford J. J Investig Med High Impact Case Rep. 2026 Jan-Dec;14:23247096261429199. doi: 10.1177/23247096261429199. Epub 2026 Mar 27. PMID: 41891177