The UNMC College of Medicine recently received grants and awards representing nearly $16 million in new funding in July. The following individuals received awards:
- Paul Sorgen, PhD, biochemistry and molecular biology, received a grant of $3,726,530 from DHHS/NIH/NIGMS for Nebraska Research Network in Functional Genomics.
- Ann Anderson-Berry, MD, PhD, pediatrics-newborn medicine, received a grant of $2,000,000 from NE DHHS-RHTP for Nebraska Perinatal Quality Improvement Collaborative: Rural Health Transformation Funds.
- Jill Poole, MD, internal medicine-allergies/immunology, received a grant of $931,110 from University of Nebraska Foundation for “UNMC College of Medicine BREATHE-10: Lung-Targeted IL-10 Therapy for Airway Inflammation.”
- Tammy Kielian, PhD, pathology, microbiology and immunology, received a grant of $603,211 from the DHHS/NIH/NIAID for a study of immune reprogramming with bioengineered scaffolds for the treatment of biofilm infection.
- Kate Hyde, PhD, biochemistry and molecular biology, received a grant of $3,726,530 from DHHS/NIH/Office of the Director for “Spectral Imaging Cell Sorter with Biosafety Cabinet.”
- Ken Bayles, PhD, pathology, microbiology and immunology, received a grant of $86,920 from DHHS/NIH/NIAID to study the role of pyruvate acquisition in the survival of Staphylococcus aureus within an intracellular environment.
- Lou Lukas, MD, internal medicine-geriatrics/palliative medicine, received a grant of $528,979 from the University of Colorado-Anschutz Medical Campus for a study of psychedelics for older adults with chronic pain.
- Siddappa Byrareddy, PhD, pharmacology and experimental neuroscience, received a grant of $422,125 from DHHS/NIH/NIA for a study of Roles of Misfolded Protein Aggregates on Latent Reservoirs in SIV-infected, ART-treated animal models.
- Rey Carabeo, PhD, pathology, microbiology and immunology, received a grant of $417,845 from DHHS/NIH/NIAID for a study of post-translational modulation of a host purine biosynthetic enzyme by Chlamydia trachomatis.
- Benita McVicker, PhD, internal medicine-GI, received a grant of $368,551 from the DHHS/NIH/NIAAA for a study of novel targeting mechanisms for alcohol-enhanced liver metastasis of colorectal cancer.
- Christopher Cummings, MD, PhD, pediatrics-genetics, received a grant of $194,292 from the DHHS/NIH/NIAAA for the study “3D Genome Disruption in Fetal Alcohol Spectrum Disorder: Toward Diagnostic and Therapeutic Targets.”
- Heather Thomas, MD, pediatrics-pulmonary, received a grant of $162,880 from the Cystic Fibrosis Foundation for the Cystic Fibrosis Care, Teaching and Research Center.
- Sarosh Rana, MD, obstetrics and gynecology, received a grant of $148,198 from the Gates Foundation for the Luteolin Road Map. Dr. Rana also received funding for the Biomarkers Registry for Investigating Data and Guiding Evaluation in Preeclampsia (BRIDGE Study).
- Ashley Deschamp, MD, pediatrics-pulmonary, received a grant of $98,243 from the Cystic Fibrosis Foundation for the Therapeutics Development Center Award. Dr. Deschamp also received a grant of $16,368 from Primary Ciliary Dyskinesia for the PCD Foundation (PCDF) Registry: A longitudinal study of patients with primary ciliary dyskinesia.
- Mithun Sattur, MBBS, neurosurgery, received a grant of $60,176 from DHHS/NIH/NINDS for the “Minimally Invasive Neuroendoscopic Ultra-Early Targeted ICH Evacuation Trial.”
- Haiying Shen, MD, PhD, pediatrics-neurology, received a grant of $50,000 from the Edna Ittner Trust-NU Foundation for the study “Developmental Brain Abnormalities in Astrocytic Glycine Transporter Deficiency: A Translational Model of Pediatric Glycinergic Encephalopathy.”
- Wei Shi, PhD, internal medicine-cardiovascular, received a grant of $50,000 from the Edna Ittner Trust-NU Foundation for the study “Targeting Disease-Driving Gene Programs in Pediatric Congenital Heart Disease.”
- Jason Michaud, MD, PhD, surgery-urologic surgery, received a grant of $49,961 from the Edna Ittner Trust-NU Foundation for the study “Intravesical Aminoglycosides for the Treatment of UTI.”
- Cyrus DeSouza, MBBS, internal medicine-DEM, received a grant of $48,943 from the VA Center-Omaha as the IPA for IMPACT. Dr. DeSouza also received funding for a study to assess the efficacy, safety, pharmacokinetics, and pharmacodynamic effects of ANGPTL3 inhibition with either small-interfering rna alone or in combination with an ANGPTL3 antibody.
- Ruxana Sadikot, MD, internal medicine-pulmonary, received a grant of $36,629 from the VA Center-Omaha as the IPA for the Better COPD-PH Study.
- Kevin Dibbern, PhD, pediatrics-sports medicine, received a grant of $29,142 from Marquette University for a study on advancing functional assessment of pediatric flatfoot using weightbearing CT.
- Joshua Mammen, MD, PhD, surgery-surgical oncology, received a grant of $25,000 from Oregon Health and Science University for the SWOG Network Group Operations Center of the NCTN.
- Zengguo Liu, MD, PhD, internal medicine-cardiovascular, received a grant of $20,242 from the University of Missouri-Columbia for a study of an implantable real-time troponin biosensor for early diagnosis of silent cardiac injuries.
- Andrea Green, MD, pediatrics-infectious diseases, received a grant of $1,000 from the Research Institute at Nationwide Children’s Hospital for dissemination of a facilitation strategy to deimplement unnecessary post-operative antibiotics at children’s hospitals.
Industry-sponsored grants and contracts.
The following industry-sponsored grants and contracts were received.
- Lindsay McAlarnen, MD, obstetrics/gynecology, received funding for a study of Sacituzumab Tirumotecan (sac-TMT, MK-2870) maintenance treatment with or without Bevacizumab vs. standard of care.
- Kelsey Klute, MD, internal medicine-oncology/hematology, received funding for a study of adjuvant Daraxonrasib vs. observation following curative intent therapy in patients with resected pancreatic ductal adenocarcinoma (PDAC) (RASolute30).
- Harshraj Leuva, MBBS, internal medicine-oncology/hematology, received funding for a study of Datopotamab Deruxtecan (Dato-DXd) plus Carboplatin or Cisplatin vs. Gemcitabine plus Carboplatin or Cisplatin in participants with locally advanced or metastatic urothelial carcinoma.
- Benjamin Tepley, MD, internal medicine-oncology/hematology, received funding for a study of INCA036873 in participants with advanced solid tumors and hematological malignancies.
- Jennifer Medlin, MD, internal medicine-rhuematology, received funding for a trial of FT819 in participants with refractory moderate-to-severe systemic lupus erythematosus with lupus nephritis.
- Sarah Holstein, MD, PhD, internal medicine-oncology/hematology, received funding for a study to evaluate the efficacy of Cemsidomide plus Dexamethasone in subjects with relapsed/refractory multiple myeloma.
- Sara Bares, MD, internal medicine-infectious diseases, received funding for “Pioneering Research to Optimize Pre-exposure Prophylaxis (PrEP) Expansion with Lenacapavir (LEN) (PROPEL).”
- Michael Facciolo, MD, pediatrics-critical care, received funding for an assessment of TruSignal SpO2 form, fit and clinical performance with infant and child patients.
- Russell McCulloh, MD, PhD, pediatrics-health systems sciences, received funding for the study of a Podocyturia based assay as a predictive biomarker for systemic vascular diseases.
- Omar Abughanimeh, MBBS, internal medicine-oncology/hematology, received funding for a study of combined Amivantamab, Carboplatin and Paclitaxel in unresectable locally recurrent or metastatic head and neck cancer.
- Ronald Zolty, MD, PhD, internal medicine-cardiovascular, received funding for a study of COR-1389 on cardiopulmonary hemodynamics in patients with pulmonary hypertension associated with left-heart disease.