Medical research highlights, August 2025

Howard Gendelman, MD

The UNMC College of Medicine recently received grants and awards representing nearly $9 million in new funding. Awards included:

  • Howard Gendelman, MD, pharmacology and experimental neuroscience, received a grant of $1,000,000 from the Michael J. Fox Foundation to study next generation Treg therapy for Parkinson’s disease.
  • Carol Geary, PhD, pathology, microbiology and immunology, received a grant of $638,400 from the University of Missouri-Columbia for “Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network — Phase 4.”
  • Robyn Moses, PhD, obstetrics and gynecology, received a grant of $225,000 from the U.S. Department of Agriculture for a study of luteal function regulation by cellular senscence signaling.
  • Kelly Stauch, PhD, neurological sciences, received a grant of $200,000 from the Parkinson’s Foundation to study new approaches for understanding dopaminergic neuron-specific mitochondrial alterations.
  • P. James Murphy, MD, internal medicine-pulmonary, received a grant of $199,730 from the Cystic Fibrosis Foundation for the CFF Center Adult Program.
  • Surinder Batra, PhD, biochemistry and molecular biology, received a grant of $189,331 from Mount Sinai Health System for the artificial-intelligence enabled stroma-weighted automated grading system to improve risk stratification in black men. Dr. Batra also received a grant of $150,000 from the U.S. Veterans Administration for “BCCMA: VA Colorectal Cancer Clinical & Computational Collaborative (VA-5C): NIR-labeled antibodies to target and label colon polyps and cancer for improved diagnosis and surgery.”
  • Andy Vasey, MD, internal medicine-general medicine, received a grant of $124,749 from West Virginia University for the RECOVER Initiative Adult Cohort.
  • Ashley Deschamp, MD, pediatrics-pulmonology, received a grant of $113,697 from the Societies for Pediatric Urology to study for the Therapeutics Development Center Award.
  • Jason Michaud, MD, PhD, surgery-urologic surgery, received a grant of $40,000 from the San Diego Biomedical Research Institute to study intravesical antibiotics for the treatment of UTI.

Industry-sponsored grants and contracts:

The following industry-sponsored grants and contracts were received.

  • Shaheed Merani, MD, PhD,  surgery-transplant, received funding for a study to evaluate the efficacy and safety of Ravulizumab administered intravenously in adult participants at high risk of delayed graft function after kidney transplantation (AWAKE).
  • Joseph Fernandes, MD, neurological sciences, received funding for a study of VHB937 in amyotrophic lateral sclerosis (ALS) over 40 weeks followed by an open-label extension.
  • Ronald Zolty, MD, PhD, internal medicine-cardiovascular, received funding for a study to evaluate the effects of Sotatercept for the treatment of combined postcapillary and precapillary pulmonary hypertension (Cpc-PH) (HARMONIZE). Dr. Zolty also received funding for a trial to assess efficacy and safety of Omecamtiv Mecarbil in patients with symptomatic heart failure with severely reduced ejection fraction.
    Shubham Agarwal, MBBS, internal medicine-DEM, received funding for a trial to evaluate liver-related clinical outcomes and safety of once weekly injected survodutide in participants with compensated non-alcoholic steatohepatitis/metabolic dysfunction.
  • Jason Cole, MD, pediatrics-cardiology, received funding for a trial to evaluate the efficacy and safety of Aficamten in a pediatric population with symptomatic obstructive hypertrophic cardiomyopathy.
  • Clifford Miles, MD, internal medicine-nephrology, received funding for assessment of BK virus T cell immunity in kidney transplant recipients.
  • Hani Haider, PhD, orthopaedic surgery, received funding for t sting of the JointMedica Polymotion.
  • Matthew Lunning, DO, internal medicine-oncology/hematology, received funding for a master protocol to evaluate the long-term safety of Pirtobrutinib.
  • Thanh Nguyen, PhD, emergency medicine, received funding for development of a low-cost hematology smear preparation system for disease diagnostic and monitoring in low-resource regions.
  • Michael Wadman, MD, emergency medicine, received funding for development of a safer and more effective skin sampling device for highly infectious skin lesions.
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