The UNMC College of Medicine received new grant and funding awards representing $4,101,722 in new funding in October.
- Keshore Bidasee, PhD, pharmacology and experimental neuroscience, received a grant of $586,400 from the Department of Health and Human Services (DHHS)/National Institutes of Health (NIH) to study diastolic dysfunction in HIV infection.
- Shannon Buckley-McKeown, PhD, genetics, cell biology and anatomy, received a grant of $110,000 from the Nebraska DHHS for a study of the regulation of stem cell fate decisions by FBXO21.
- Keely Buesing, MD, surgery-general surgery, received a grant of $112,225 from the University of Colorado-Boulder to study peritoneal oxygen delivery for the treatment of acute respiratory distress syndrome.
- Amy Cannella, MD, internal medicine-rheumatology, received the 2022 Rheumatology Research Foundation Amgen Fellowship Training Award of $50,000 from the Rheumatology Research Foundation.
- Donald Coulter, MD, pediatrics-hematology/oncology, received two grants totaling $11,000 from Children’s Hospital of Philadelphia for two work orders: Reducing risk of Anthracycline-related heart failure after childhood cancer, and one time EOY, integrated BIQSFP AAML1031-echocardiogram reports and images.
- Alfred Fisher, MD, internal medicine-geriatrics, received a grant of $406,700 from Duke University for the study “Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults (PREVENTABLE).
- Diana Florescu, MD, internal medicine-infectious diseases, received a grant of $153,000 from the Fred Hutchinson Cancer Center for COVID-19 Prevention Network (CoVPN) site preparedness funding.
- Howard Gendelman, MD, pharmacology and experimental neuroscience, received a grant of $138,123 from the Scripps Research Foundation for a study of long-acting GM-CSF fusion protein (PDM608) for the treatment of Parkinson’s disease.
- Santhi Gorantla, PhD, pharmacology and experimental neuroscience, received a grant of $2,000 from DHHS/NIH for preclinical services for HIV therapeutics.
- Kusum Kharbanda, PhD, internal medicine-GI, received a grant of $62,269 from the VA Medical Center-Omaha for an IPA study of impaired methylation alters lipid droplet dynamics in liver and adipose tissue: role in hepatic steatosis.
- James McClay, MD, emergency medicine, received a grant of $17,401 from the University of Kansas Medical Center for a study on identifying personalized risk of acute kidney injury with machine learning.
- James Murphy, MD, internal medicine-pulmonary, received a grant of $149,520 from the Cystic Fibrosis Foundation (CFF) for a CFF center adult program.
- Jingwei Xie, PhD, surgery-transplant, received a grant of $83,875 from the University of Rochester for a study of engineering structural bone allografts for enhanced repair and reconstruction.
Industry-sponsored grants and contracts:
The following industry-sponsored contracts and foundation grants were received. Information on clinical trials enrolling patients at UNMC can be found here.
- Sara Bares, MD, internal medicine-infectious diseases, received funding for a phase 4, randomized, active-controlled, open-label study to evaluate the safety and tolerability of switching to once-daily Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) fixed-dose combination (FDC) regimen.
- Vijaya Bhatt, MD, internal medicine-oncology/hematology, received funding for V-FAST: A phase 1b master trial to investigate CPX-351 combined with various targeted agents in subjects with previously untreated acute myeloid leukemia.
- Andre Kalil, MD, internal medicine-infectious diseases, received funding for a double-blind, randomized, placebo-controlled, phase 1, single-dose, dose-escalating trial of long-acting recombinant human IL-7 (NT-I7) for COVID-19 (COVID-19 SPESELPIS).
- Avyakta Kallam, MD, internal medicine-oncology/hematology, received funding for a phase 1, open-label study of Voruciclib in subjects with relapsed and/or refractory B cell malignancies or acute myeloid leukemia after failure of prior standard therapies.
- Ronald Krueger, MD, ophthalmology and visual sciences, received funding for a pivotal trial of WaveLight EX500 Excimer Laser System for the correction of myopia with and without astigmatism using InnovEyes in conjunction with InnovEyes.
- Matthew Lunning, DO, internal medicine-oncology/hematology, received funding for a phase 1, multicenter, open-label study of CC-97540, CD19-targeted NEX-T chimeric antigen receptor (CAR) T cells, in subjects with relapsed or refractory B-cell non-Hodgkin lymphoma (NEX-T CAR-T).
- Joshua Santarpia, PhD, pathology/microbiology, received funding for SD 90+ decontaminant solution viral testing.
- Aleem Siddique, MBBS, surgery-cardiothoracic surgery, received funding for a prospective, randomized , active (warfarin) controlled, parallel-arm clinical trial to determine if patients with an On-X aortic valve can be maintained safely and effectively on the factor Xa inhiitor apixaban.
- Austin Thompson, MD, internal medicine-pulmonary, received funding for a study evaluating the long-term efficacy and safety of Ralinepag in subjects with PAH via an open-label extension (Advance Extension)