- Core Facility Directory
- Clinical Research Resources
- Nebraska Biobank
- Grant Editing Support
- Grant Resource Library
- Centers and Major Programs
- Sponsored Programs Administration (SPA)
- Comparative Medicine
- Government Relations
- Intellectual Property Assistance
- Inter-Campus Shuttle
- Translational Cores
- Advanced Microscopy Core Facility
- Animal Behavior Core
- Biosafety Level 3 (BSL-3) Core Facility
- Computational Chemistry
- Electron Microscopy
- Epigenomics Core Facility (ECF)
- Flow Cytometry Research Facility
- Genomics Core Facility
- Human Magnetic Resonance Imaging
- Mass Spectrometry and Proteomics Core Facility
- Mouse Genome Engineering Core
- Nanoimaging Core Facility
- Small Animal Imaging
- Translational Mouse Model Core Facility
- Core Facility Scheduling and Billing
This facility was established with an R24 grant ("Center for Humanized Mice" R24OD018546) from the Office of the Director of the National Institutes of Health.
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Santhi Gorantla, PhDCo-Director |
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Larisa Poluektova, PhDCo-Director |
At UNMC Drs. Larisa Poluektova and Santhi Gorantla have been working on humanized mice for past 12 years and pioneered novel humanized mouse model with functional human immune system for the studies of NeuroAIDS and with human liver for HIV-1 and HCV co-infections (published work).
Their expertise in this mouse model ensued in procuring an R24 NIH grant to further genetically modify NSG strain, with the help of Dr. Channabasavaiah Gurumurthy (Director of Mouse genomics), to improve the accommodation of human immune system in mice for vaccine development and to include human drug metabolizing enzymes in NSG mice for drug interaction studies.
This facility was established through an R24 grant from the National Institutes of Health.
Please acknowledge:
Office of the Director of the National Institutes of Health award
R24OD018546
"Center for Humanized Mice"
in all publications, press releases, and applications that have used this facility either directly or collaboratively.
- Core Facility Directory
- Clinical Research Resources
- Nebraska Biobank
- Grant Editing Support
- Grant Resource Library
- Centers and Major Programs
- Sponsored Programs Administration (SPA)
- Comparative Medicine
- Government Relations
- Intellectual Property Assistance
- Inter-Campus Shuttle
- Translational Cores
- Advanced Microscopy Core Facility
- Animal Behavior Core
- Biosafety Level 3 (BSL-3) Core Facility
- Computational Chemistry
- Electron Microscopy
- Epigenomics Core Facility (ECF)
- Flow Cytometry Research Facility
- Genomics Core Facility
- Human Magnetic Resonance Imaging
- Mass Spectrometry and Proteomics Core Facility
- Mouse Genome Engineering Core
- Nanoimaging Core Facility
- Small Animal Imaging
- Translational Mouse Model Core Facility
- Core Facility Scheduling and Billing