Department of Internal Medicine faculty publish in a wide variety of journals and on topics pertaining to all our divisions. Special thanks to all faculty, house officers, postdoctoral fellows, students, and staff who perform and support the research mission of the department. We also thank those who serve on the Internal Medicine Research Council (IMRC) for their research advocacy and research training efforts. We obtained the data for this report from ADIS and Scopus. Please contact us if you have questions.
Notable Publications - 1st Quarter 2021
Cardiology
Diabetes, Endocrinology, and Metabolism
Gastroenterology & Hepatology
General Internal Medicine
Geriatrics & Palliative Medicine
Hematology & Oncology
Infectious Diseases
Nephrology
Pulmonary, Critical Care & Sleep Medicine
Rheumatology
Cardiology
Albulushi A., Olson J., Xie F., Qian L., Mathers D., Aboeata A., Porter T.R.; Effect of Intermittent High–Mechanical Index Impulses on Left Ventricular Strain; Journal of the American Society of Echocardiography
*Selected as one of the UNMC Department of Internal Medicine Honorable Mention Publication – 1st Quarter 2021
Jhand A., Atti V., Gwon Y., Dhawan R., Turagam M.K., Mamas M.A., Brilakis E.S., Kumar A., Katta N., Chatzizisis Y., Parikh M., Abbott J.D., Kirtane A.J., Bhatt D.L., Velagapudi P.; Meta-Analysis of Transradial vs Transfemoral Access for Percutaneous Coronary Intervention in Patients With ST Elevation Myocardial Infarction; American Journal of Cardiology
Lundgren S.W., Florescu D.F., Zolty R.; Reactivation of Cytomegalovirus Following Left Ventricular Assist Device Implantation: A Case-Control Study; ASAIO journal (American Society for Artificial Internal Organs : 1992)
Diabetes, Endocrinology, and Metabolism
Hanna KM, Kupzyk KA, Hansen JR, Jones-Ryan ML, Drincic AT; Association of habits, triggers, glycaemic control, routines, stress and impulse control among emerging adults with type 1 diabetes; Diabetic Medicine
Gastroenterology & Hepatology
Rasineni K., Jordan C.W., Thomes P.G., Kubik J.L., Staab E.M., Sweeney S.A., Talmon G.A., Donohue T.M., McNiven M.A., Kharbanda K.K., Casey C.A.; Contrasting Effects of Fasting on Liver-Adipose Axis in Alcohol-Associated and Non-alcoholic Fatty Liver; Frontiers in Physiology
*Selected as one of the UNMC Department of Internal Medicine Honorable Mention Publication – 1st Quarter 2021
Dagur R.S., New-Aaron M., Ganesan M., Wang W., Romanova S., Kidambi S., Kharbanda K.K., Poluektova L.Y., Osna N.A.; Alcohol-and-hiv-induced lysosomal dysfunction regulates extracellular vesicles secretion in vitro and in liver-humanized mice; Biology
Rasineni K., Lee S.M.L., McVicker B.L., Osna N.A., Casey C.A., Kharbanda K.K.; Susceptibility of asialoglycoprotein receptor-deficient mice to lps/galactosamine liver injury and protection by betaine administration; Biology
General Internal Medicine
Richards S., Carlson K., Matthias T., Birge J.; Perception versus reality: Does provider documentation behavior change when clinic notes are shared electronically with patients?; International Journal of Medical Informatics
Geriatrics & Palliative Medicine
Koll T.T., Semin J.N., Brodsky R., Keehn D., Fisher A.L., High R., Beadle J.N.; Health-related and sociodemographic factors associated with physical frailty among older cancer survivors; Journal of Geriatric Oncology
Hematology & Oncology
Bhatt V.R., Dhakal P., Wichman C.S., Pozehl B.; Development and validation of the Therapy Preference Scale to understand patientś systemic cancer treatment preferences; Future Oncology
Haney S.L., Varney M.L., Chhonker Y., Talmon G., Smith L.M., Murry D.J., Holstein S.A.; In vivo evaluation of combination therapy targeting the isoprenoid biosynthetic pathway; Pharmacological Research
Infectious Diseases
Demers A.-M., Kim S., McCallum S., Eisenach K., Hughes M., Naini L., Mendoza-Ticona A., Pradhan N., Narunsky K., Poongulali S., Badal-Faesen S., Upton C., Smith E., Shah N.S., Churchyard G., Gupta A., Hesseling A., Swindells S., for the ACTG A5300/IMPAACT I200; Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial; BMC Infectious Diseases
Florescu D.F., Seaman J.A., Kalil A.C., Qiu F., Bremers D., Westphal S.G.; Opportunistic Infections After Induction With Alemtuzumab or Basiliximab: A 3-Year Kidney Transplantation Experience; Transplantation Proceedings
Rearigh L.M., Hewlett A.L., Fey P.D., Broadhurst M.J., Brett-Major D.M., Rupp M.E., Van Schooneveld T.C.; Utility of repeat testing for COVID-19: Laboratory stewardship when the stakes are high; Infection Control and Hospital Epidemiology
Nephrology
Ang A., Schieve C., Rose S., Kew C., First M.R., Mannon R.B.; Avoiding surveillance biopsy: Use of a noninvasive biomarker assay in a real-life scenario; Clinical Transplantation
Florescu M.C., Plumb T.J., Westphal S., Mullane R., Reilly D.A.; Liposuction used to treat deep vascular accesses for hemodialysis; Journal of Vascular Access
Plumb T.J., Alvarez L., Ross D.L., Lee J.J., Mulhern J.G., Bell J.L., Abra G.E., Prichard S.S., Chertow G.M., Aragon M.A.; Self-care training using the Tablo hemodialysis system; Hemodialysis International
Pulmonary, Critical Care & Sleep Medicine
Gaurav R., Mikuls T.R., Thiele G.M., Nelson A.J., Niu M., Guda C., Eudy J.D., Barry A.E., Wyatt T.A., Romberger D.J., Duryee M.J., England B.R., Poole J.A.; High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis; PLoS ONE
Krutsinger D; Hetland BD; O Leary KL; Halpern SD; Courtright KR; A qualitative analysis of factors influencing critical care trial enrollment among surrogates; Journal of intensive care medicine
Rheumatology
England B.R., Roul P., Yang Y., Sayles H., Yu F., Michaud K., Xie F., Curtis J.R., Mikuls T.R.; Burden and trajectory of multimorbidity in rheumatoid arthritis: A matched cohort study from 2006 to 2015; Annals of the Rheumatic Diseases
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 1st Quarter 2021
Cardiology
Diabetes, Endocrinology, and Metabolism
Gastroenterology & Hepatology
General Internal Medicine
Hematology & Oncology
Infectious Disease
Nephrology
Rheumatology
Cardiology
Wu W., Samant S., de Zwart G., Zhao S., Khan B., Ahmad M., Bologna M., Watanabe Y., Murasato Y., Burzotta F., Brilakis E.S., Dangas G., Louvard Y., Stankovic G., Kassab G.S., Migliavacca F., Chiastra C., Chatzizisis Y.S.; 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility; Scientific Reports
Shaohua Wu; Vikas Kumar; Peng Xiao; Mitchell Kuss; Jung Yul Lim; Chittibabu Guda; Jonathan Butcher; Bin Duan; Age related extracellular matrix and interstitial cell phenotype in pulmonary valves; Scientific Reports
Diabetes, Endocrinology, and Metabolism
Kotwal A., Gustafson M.P., Bornschlegl S., Kottschade L., Delivanis D.A., Dietz A.B., Gandhi M., Ryder M.; Immune Checkpoint Inhibitor-Induced Thyroiditis Is Associated with Increased Intrathyroidal T Lymphocyte Subpopulations; ThyroidGastroenterology & Hepatology
Murali Ganesan; Saumi Mathews; Edward Makarov; Armen Petrosyan; Kusum Kharbanda; Srivatsan S Kidambi; Larisa Y Poluektova; Carol A. Casey; Natalia A Osna; Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation; American journal of Physiology. Gastrointestinal and Liver Physiology
Korbitz P.M., Gallagher J.P., Samant H., Singh S., Jophlin L., Ingviya T., Manatsathit W.; Performance of echocardiography for detection of portopulmonary hypertension among liver transplant candidates: Meta-analysis; Clinical Transplantation
General Internal Medicine
Smith C.J., Matthias T., Beam E., Wampler K., Pounds L., Nickol D., Shope R.J., Carlson K., Michael K.; A Mixed-Methods Evaluation of Medical Residents’ Attitudes Towards Interprofessional Learning and Stereotypes Following Sonography Student-Led Point-of-Care Ultrasound Training; Journal of General Internal Medicine
Kratochvil T.J., Khazanchi R., Sass R.M., Caverzagie K.J.; Aligning student-led initiatives and Incident Command System resources in a pandemic; Medical Education
Hematology & Oncology
Dhakal P., Lyden E., Muir K.-L.E., Al-Kadhimi Z.S., Maness L.J., Gundabolu K., Bhatt V.R.; Effects of Distance From Academic Cancer Center on Overall Survival of Acute Myeloid Leukemia: Retrospective Analysis of Treated Patients; Clinical Lymphoma, Myeloma and Leukemia
Dhakal P., Shostrom V., Al-Kadhimi Z.S., Maness L.J., Gundabolu K., Bhatt V.R.; Usefulness of Charlson Comorbidity Index to Predict Early Mortality and Overall Survival in Older Patients With Acute Myeloid Leukemia; Clinical Lymphoma, Myeloma and Leukemia
Infectious Disease
Van Schooneveld T.C., Rupp M.E., Jenifer Cavaleiri R., Lyden E., Rolek K.; Cluster randomized trial of an antibiotic time-out led by a team-based pharmacist; Infection Control and Hospital Epidemiology
Hanna K.F., Sayles H.R., O’Neill J., White M.L., Wilson T.W., Swindells S.; Incidental Findings on Brain MRI in People with HIV Infection; Scientific Reports
Rearigh L., O’Neill J., Kubat M., Sayles H., Swindells S., Bares S.H.; Surprisingly low levels of measles immunity in persons with HIV: A seroprevalence survey in a United States HIV clinic; Open Forum Infectious Diseases
Kalil AC, Patterson TF, Mehta AK, Tomashek KM, Wolfe CR, Ghazaryan V, Marconi VC, Ruiz-Palacios GM, Hsieh L, Kline S, Tapson V, Iovine NM, Jain MK, Sweeney DA, El Sahly HM, Branche AR, Regalado Pineda J, Lye DC, Sandkovsky U, Luetkemeyer AF, Cohen SH, Finberg RW, Jackson PEH, Taiwo B, Paules CI, Arguinchona H, Goepfert P, Ahuja N, Frank M, Oh MD, Kim ES, Tan SY, Mularski RA, Nielsen H, Ponce PO, Taylor BS, Larson L, Rouphael NG, Saklawi Y, Cantos VD, Ko ER, Engemann JJ, Amin AN, Watanabe M, Billings J, Elie MC, Davey RT, Burgess TH, Ferreira J, Green M, Makowski M, Cardoso A, de Bono S, Bonnett T, Proschan M, Deye GA, Dempsey W, Nayak SU, Dodd LE, Beigel JH; Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19; New England Journal of Medicine
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 4th Quarter 2020
Nephrology
Mannon R.B., Armstrong B., Stock P.G., Mehta A.K., Farris A.B., Watson N., Morrison Y., Sarwal M., Sigdel T., Bridges N., Robien M., Newell K.A., Larsen C.P.; Avoidance of CNI and steroids using belatacept—Results of the Clinical Trials in Organ Transplantation 16 trial; American Journal of Transplantation
Rheumatology
Mikuls T.R., Edison J., Meeshaw E., Sayles H., England B.R., Duryee M.J., Hunter C.D., Kelmenson L.B., Kay Moss L., Feser M.L., Wagner B., Parish M.C., Deane K.D., Thiele G.M.; Autoantibodies to Malondialdehyde–Acetaldehyde Are Detected Prior to Rheumatoid Arthritis Diagnosis and After Other Disease Specific Autoantibodies; Arthritis and Rheumatology
England B.R., Roul P., Mahajan T.D., Singh N., Yu F., Sayles H., Cannon G.W., Sauer B.C., Baker J.F., Curtis J.R., Mikuls T.R.; Performance of Administrative Algorithms to Identify Interstitial Lung Disease in Rheumatoid Arthritis; Arthritis Care and Research
Luedders B.A., Johnson T.M., Sayles H., Thiele G.M., Mikuls T.R., O'Dell J.R., England B.R.; Predictive ability, validity, and responsiveness of the multi-biomarker disease activity score in patients with rheumatoid arthritis initiating methotrexate; Seminars in Arthritis and Rheumatism
Notable Publications - 3rd Quarter 2020
Cardiology
Gastroenterology & Hepatology
Hematology & Oncology
Infectious Disease
Pulmonary, Critical Care, Sleep Medicine
Rheumatology
Cardiology
Atti, V., Gwon, Y., Narayanan, M.A., Garcia, S., Sandoval, Y., Brilakis, E.S., Basir, M.B., Turagam, M.K., Khandelwal, A., Mena-Hurtado, C., Mamas, M.A., Abbott, J.D., Bhatt, D.L., Velagapudi, P.; Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease: Meta-Analysis of Randomized Trials; JACC: Cardiovascular Interventions
Goldsweig, A.M., Lyden, E., Aronow, H.D., Kolte, D., Pavlides, G., Barton, D., Chatzizisis, Y., Gumina, R.J., Abbott, J.D.; Impact of Age on Patients' Communication and Technology Preferences in the Era of Meaningful Use: Mixed Methods Study; Cardiology (Switzerland)
Jiang, X., Wu, S., Kuss, M., Kong, Y., Shi, W., Streubel, P.N., Li, T., Duan, B.; 3D printing of multilayered scaffolds for rotator cuff tendon regeneration, Bioactive Materials
Gastroenterology & Hepatology
Peter S., Pendergraft A., VanDerPol W., Wilcox C.M., Kyanam Kabir Baig K.R., Morrow C., Izard J., Mannon P.J.; Mucosa-Associated Microbiota in Barrett's Esophagus, Dysplasia, and Esophageal Adenocarcinoma Differ Similarly Compared With Healthy Controls Clinical and Translational Gastroenterology
McVicker B.L., Hamel F.G., Simpson R.L., Bennett R.G.; A selective PPARγ modulator reduces hepatic fibrosis, Biology
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 3rd Quarter 2020
Hematology & Oncology
Holstein S.A., Suman V.J., Owzar K., Santo K., Benson D.M., Jr., Shea T.C., Martin T., Silverman M., Isola L., Vij R., Cheson B.D., Linker C., Anderson K.C., Richardson P.G., McCarthy P.L.; Long-Term Follow-up of CALGB (Alliance) 100001: Autologous Followed by Nonmyeloablative Allogeneic Transplant for Multiple Myeloma, Biology of Blood and Marrow Transplantation
Grinnell M., Appiah A.K., Baine M., Ernani V., Marr A., Zhang C., Zhen W., Buddharaju L.N.R., Smith L.M., Ganti A.K.; Adjuvant chemotherapy following SBRT for early stage non-small cell lung cancer (NSCLC) in older patients, Journal of Geriatric Oncology
Infectious Disease
Rearigh L., Stohs E., Freifeld A., Zimmer A.; Advanced Preparation Makes Research in Emergencies and Isolation Care Possible: The Case of Novel Coronavirus Disease (COVID-19); Annals of Hematology
Pulmonary, Critical Care, Sleep Medicine
Bailey K.L., Smith H., Mathai S.K., Huber J., Yacoub M., Yang I.V., Wyatt T.A., Kechris K., Burnham E.L.; Alcohol Use Disorders Are Associated With a Unique Impact on Airway Epithelial Cell Gene Expression, Alcoholism: Clinical and Experimental Research
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 3rd Quarter 2020
Rheumatology
Mikuls T.R., Johnson S.R., Fraenkel L., Arasaratnam R.J., Baden L.R., Bermas B.L., Chatham W., Cohen S., Costenbader K., Gravallese E.M., Kalil A.C., Weinblatt M.E., Winthrop K., Mudano A.S., Turner A., Saag K.G.; American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID-19 Pandemic: Version 1, Arthritis and Rheumatology
Chiou A., England B.R., Sayles H., Thiele G.M., Duryee M.J., Baker J.F., Singh N., Cannon G.W., Kerr G.S., Reimold A., Gaffo A., Mikuls T.R.; Coexistent Hyperuricemia and Gout in Rheumatoid Arthritis: Associations With Comorbidities, Disease Activity, and Mortality, Arthritis Care and Research
Notable Publications - 2nd Quarter 2020
Allergy & Immunology
Cardiology
Diabetes, Endocrinology, Metabolism
Gastroenterology & Hematology
Geriatrics
General Internal Medicine
Hematology & Oncology
Infectious Disease
Rheumatology
Allergy & Immunology
Johnson A.N., Harkema J.R., Nelson A.J., Dickinson J.D., Kalil J., Duryee M.J., Thiele G.M., Kumar B., Singh A.B., Gaurav R., Glover S.C., Tang Y., Romberger D.J., Kielian T., Poole J.A.; MyD88 regulates a prolonged adaptation response to environmental dust exposure-induced lung disease, Respiratory Research
Cardiology
Lundgren S., Lowes B., Lyden E., Zolty R., Hyden M., Burdorf A., Um J.Y., Stoller D.; Pre-Heart Transplant Spirometry Predicts Post-Transplant Survival; Journal of Heart and Lung Transplantation
Clarke M.A., Fruhling A.L., Sitorius M., Windle T.A., Bernard T.L., Windle J.R.; Impact of Age on Patients' Communication and Technology Preferences in the Era of Meaningful Use: Mixed Methods Study; Journal of Medical Internet Research
Diabetes, Endocrinology, Metabolism
Thiyagarajan Thangavelu; Elizabeth Lyden; Vijay Shivaswamy; Prospective Study of Glucagon-Like Peptide‚ 1 Receptor Agonists for the Management of Diabetes After Transplantation, Diabetes Therapy
Gastroenterology & Hematology
Arumugam M.K., Talawar S., Listenberger L., Donohue T.M., Jr, Osna N.A., Kharbanda K.K.; Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease, Cells
Geriatrics
Koll T; Semin JN; Brodsky RA; Keehn DC; Fisher AL; High RR; Beadle JN; Health-related and sociodemographic factors associated with physical frailty among older cancer survivors, Journal of Geriatric Oncology
General Internal Medicine
Antoniak D.T., Benes B.J., Hartman C.W., Vokoun C.W., Samson K.K., Shiffermiller J.F.; Impact of Chronic Kidney Disease in Older Adults Undergoing Hip or Knee Arthroplasty: A Large Database Study, Journal of Arthroplasty
Mahabir C.A., Anderson M., Cimino J., Lyden E., Siahpush M., Shiffermiller J.; Derivation and validation of a multivariable model, the alcohol withdrawal triage tool (AWTT), for predicting severe alcohol withdrawal syndrome, Drug and Alcohol Dependence
Hematology & Oncology
Bhatt V.R., Shostrom V., Holstein S.A., Al-Kadhimi Z.S., Maness L.J., Berger A., Armitage J.O., Gundabolu K.; Survival of Older Adults With Newly Diagnosed Acute Myeloid Leukemia: Effect of Using Multiagent Versus Single-agent Chemotherapy, Clinical Lymphoma, Myeloma and Leukemia
Infectious Disease
Brett-Major DM; Schnaubelt ER; Creager HM; Lowe AE; Cieslak TJ; Dahlke JM; johnson dw; Fey PD; Hansen KF; Angela Hewlett; Gordon BG; Kalil AC; Khan AS; Kortepeter MG; Linder J; Meaker-Medcalf SJ; Rupp ME; Schwedhelm MM; Sullivan JA; Vasa AM; Wadman MC; Lookadoo RE; Lowe JJ; Lawler JV; Broadhurst MJ; Advanced Preparation Makes Research in Emergencies and Isolation Care Possible: The Case of Novel Coronavirus Disease (COVID-19); The American journal of Tropical Medicine and Hygiene
Rheumatology
Thiele G.M., Duryee M.J., Hunter C.D., England B.R., Fletcher BS, Daubach E.C., Pospisil T.P., Klassen L.W., Mikuls T.R.; Immunogenic and inflammatory responses to citrullinated proteins are enhanced following modification with malondialdehyde-acetaldehyde adducts, International ImmunopharmacologyNotable Publications - 1st Quarter 2020
Allergy & Immunology
Cardiology
Diabetes, Endocrinology, Metabolism
Geriatrics
Infectious Disease
Nephrology
Oncology
Pulmonary, Critical Care, and Sleep
Rheumatology
Allergy & Immunology
Jill A. Poole, Tara M. Nordgren, Art J. Heires, Amy J. Nelson, Dawn Katafiasz, Kristina L. Bailey, and Debra J. Romberger; Amphiregulin modulates murine lung recovery and fibroblast function following exposure to agriculture organic dust; American Journal of Physiology-Lung Cellular and Molecular Physiology
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication– 1st Quarter 2020
Cardiology
Wu S, Zhou R, Zhou F, Streubel PN, Chen S, Duan B.; Electrospun thymosin Beta-4 loaded PLGA/PLA nanofiber/ microfiber hybrid yarns for tendon tissue engineering application. Materials Science Engineering C; Material for Biological Applications
Arif Albulushi, Andrew M. Goldsweig, Douglas Stoller, Jeffrey W. Delaney, John Um, Brian Lowes, Ronald Zolty; Percutaneous Deactivation of Left Ventricular Assist Devices; Seminars in Thoracic and Cardiovascular Surgery
Diabetes, Endocrinology, Metabolism
Laura A Graeff-Armas, Igor Bendik, Iris Kunz, Rotraut Schoop, Sarah Hull, Mareike Beck, Supplemental 25-Hydroxycholecalciferol Is More Effective than Cholecalciferol in Raising Serum 25-Hydroxyvitamin D Concentrations in Older Adults, The Journal of Nutrition
Cyrus DeSouza, Bertrand Cariou, Satish Garg, Nanna Lausvig, Andrea Navarria, Vivian Fonseca, Efficacy and Safety of Semaglutide for Type 2 Diabetes by Race and Ethnicity: A Post Hoc Analysis of the SUSTAIN Trials, The Journal of Clinical Endocrinology & Metabolism
Geriatrics
Thuy T. Koll, Jessica N. Semin, Rachel A. Coburn, Diane M. Hill-Polerecky, Kimberly A. Miller, Tanya M. Wildes, Paul A. Estabrooks, Katherine J. Jones; Returning to life activities after hematopoietic cell transplantation in older adults; Journal of Geriatric Oncology
Thuy T. Koll, Amelia Nelson Sheese, Jessica Semin, Weston Ernst, Robin High, Tanya M. Wildes, Alfred Fisher, Daniel L. Murman; Screening for cognitive impairment in older adults with hematological malignancies using the Montreal Cognitive Assessment and neuropsychological testing; Journal of Geriatric Oncology
Infectious Disease
Muhammad S. Ashraf, Swati Gaur, Oluma Y. Bushen, Teena Chopra, Philip Chung, Kalin Clifford, Elizabeth Hames, Cees M.P.M. Hertogh, Amar Krishna, Dheeraj Mahajan, David R. Mehr, Vycki Nalls, Theresa Ann Rowe, Steven J. Schweon, Philip D. Sloane, Kavita K. Trivedi, Laura W. van Buul, Robin L.P. Jump; Diagnosis, Treatment, and Prevention of Urinary Tract Infections in Post-Acute and Long-Term Care Settings: A Consensus Statement From AMDA's Infection Advisory Subcommittee; Journal of the American Medical Directors Association
Susan Swindells, Jaime Federico, Andrade Villanueva, Gary J Richmond, Giuliano Rizzardini, Axel Baumgarten, Mar Masiá, Gulam Latiff, Vadim Pokrovsky, Fritz Bredeek, Graham Smith, Pedro Cahn, Yeon Sook Kim, Susan L Ford, Christine L Talarico, Parul Patel, Vasiliki Chounta, Herta Crauwels, Wim Parys, Simon Vanveggel, Joseph Mrus, Jenny Huang, Harrington, Conn M, Hudson, Krischan J, David A Margolis, Kimberly Y Smith, Peter E Williams, William R Spreen; Long Acting Cabotegravir and Rilpivirine for Maintenance of HIV1 Suppression; New England Journal of Medicine
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter - 1st Quarter 2020
Nephrology
Plumb TJ, Alvarez L, Ross DL, et al. Safety and efficacy of the Tablo hemodialysis system for in-center and home hemodialysis. Hemodialysis International
Oncology
Vijaya R. Bhatt, Valerie Shostrom, Sarah A. Holstein, Zaid S. Al-Kadhimi, Lori J. Maness, Ann Berger, James O. Armitage, Krishna Gundabolu; Survival of Older Adults With Newly Diagnosed Acute Myeloid Leukemia: Effect of Using Multiagent Versus Single-agent Chemotherapy; Clinical Lymphoma Myeloma and Leukemia
Pulmonary, Critical Care, and Sleep
Bailey KL, Murphy PJ, Lineberry OK, et al; Procalcitonin predicts the severity of cystic fibrosis pulmonary exacerbations and readmissions in adult patients: a prospective cohort study; Journal of Investigative Medicine
Rheumatology
Rohlfsen, C. J., Sayles, H., Moore, G. F., Mikuls, T. R., O'Dell, J. R., McBrien, S., Johnson, T., Fowler, Z. D., & Cannella, A. C.; Innovation in early medical education, no bells or whistles required. BMC Medical EducationNotable Publications - 4th Quarter 2019
Cardiology
Gastroenterology
Geriatrics
Infectious Disease
Oncology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology
Cardiology
Wei L., Wu S., Kuss M., Jiang X., Sun R., Reid P., Qin X., Duan B.; 3D printing of silk fibroin-based hybrid scaffold treated with platelet rich plasma for bone tissue engineering, Bioactive Materials
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication– 4th Quarter 2019
Liu X., Clemens D.L., Grunkemeyer J.A., Price J.D., O’Connell K., Chapman N.M., Storz P., Wen H., Cox J.L., Reid W.L., Hollingsworth M.A., Thayer S., Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis, Scientific Reports
Basma H., Johanson A.N., Dhar K., Anderson D., Qiu F., Rennard S., Lowes B.D., TGF-β induces a heart failure phenotype via fibroblasts exosome signaling, Heliyon
Gastroenterology
Ganesan M., New-Aaron M., Dagur R.S., Makarov E., Wang W., Kharbanda K.K., Kidambi S., Poluektova L.Y., Osna N.A., Alcohol metabolism potentiates HIV-induced hepatotoxicity: Contribution to end-stage liver disease, biomolecules
Geriatrics
Koll TT; Semin JN; Coburn RA; Hill-Polerecky DM; Miller KA; Wildes, Tanya M.; Estabrooks PA; Jones KJ; Returning to life activities after hematopoietic cell transplantation in older adults; Journal of Geriatric Oncology
Infectious Disease
Hankins R., Majorant O.D., Rupp M.E., Cavalieri R.J., Fey P.D., Lyden E., Cawcutt K.A.; Microbial colonization of intravascular catheter connectors in hospitalized patients; American Journal of Infection Control
Oncology
Lunning M., Vose J., Nastoupil L., Fowler N., Burger J.A., Wierda W.G., Schreeder MT, Siddiqi T., Flowers C.R., Cohen J.B., Sportelli P., Miskin H.P., Weiss MS, O'Brien S.; Ublituximab and umbralisib in relapsed/refractory B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia; blood
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter - 4th Quarter 2019
Pulmonary, Critical Care, Sleep and Allergy
Samuelson D.R., Gu M., Shellito J.E., Molina P.E., Taylor C.M., Luo M., Welsh D.A.; Intestinal Microbial Products From Alcohol-Fed Mice Contribute to Intestinal Permeability and Peripheral Immune Activation; Alcoholism: Clinical and Experimental Research
Bailey K.L., Wyatt T.A., Katafiasz D.M., Taylor K.W., Heires A.J., Sisson J.H., Romberger D.J., Burnham E.L.; Alcohol and cannabis use alter pulmonary innate immunity; Alcohol
Samuelson D.R., Siggins R.W., Ruan S., Amedee A.M., Sun J., Zhu Q.K., Marasco W.A., Taylor C.M., Luo M., Welsh D.A., Shellito J.E.; Alcohol consumption increases susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis; Alcohol
Price M.E., Gerald C.L., Pavlik J.A., Schlichte S.L., Zimmerman M.C., DeVasure J.M., Wyatt T.A., Sisson J.H.; Loss of cAMP-dependent stimulation of isolated cilia motility by alcohol exposure is oxidant-dependent; Alcohol
Rheumatology
Maloley P.M., England B.R., Sayles H., Thiele G.M., Michaud K., Sokolove J., Cannon G.W., Reimold A.M., Kerr G.S., Baker J.F., Caplan L., Case A.J., Mikuls T.R.; Post-traumatic stress disorder and serum cytokine and chemokine concentrations in patients with rheumatoid arthritis; Seminars in Arthritis and Rheumatism
England B.R., Tiong B.K., Bergman M.J., Curtis J.R., Kazi S., Mikuls T.R., O'Dell J.R., Ranganath V.K., Limanni A., Suter L.G., Michaud K.; 2019 Update of the American College of Rheumatology Recommended Rheumatoid Arthritis Disease Activity Measures; Arthritis Care and Research
Johnson T.M., Register K.A., Schmidt C.M., O'Dell J.R., Mikuls T.R., Michaud K., England B.R.; Correlation of the Multi-Biomarker Disease Activity Score With Rheumatoid Arthritis Disease Activity Measures: A Systematic Review and Meta-Analysis; Arthritis Care and Research
Notable Publications - 3rd Quarter 2019
Cardiology
Gastroenterology
Nephrology
Oncology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology
Cardiology
Barton D., Xie F., O'Leary E., Chatzizisis Y.S., Pavlides G., Porter T.R.; The Relationship of Capillary Blood Flow Assessments with Real Time Myocardial Perfusion Echocardiography to Invasively Derived , Journal of the American Society of Echocardiography
Goldsweig A.M., Tak H.J., Chen L.-W., Aronow H.D., Shah B., Kolte D.S., Velagapudi P., Desai N., Szerlip M., Abbott J.D., The Evolving Management of Aortic Valve Disease: 5-Year Trends in SAVR, TAVR, and Medical Therapy, American Journal of Cardiology
Gastroenterology
Ganesan M., Krutik V.M., Makarov E., Mathews S., Kharbanda K.K., Poluektova L.Y., Casey C.A., Osna N.A.;Acetaldehyde suppresses the display of HBV-MHC class I complexes on HBV-expressing hepatocytes; American Journal of Physiology - Gastrointestinal and Liver Physiology
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter - 3rd Quarter 2019
Rasineni K., Kubik J.L., Casey C.A., Kharbanda K.K.; Inhibition of Ghrelin Activity by Receptor Antagonist [d-Lys-3] GHRP-6 Attenuates Alcohol-Induced Hepatic Steatosis by Regulating Hepatic Lipid Metabolism, Biomolecules
Nephrology
Mullane R., Fristoe L., Markin N.W., Brakke T.R., Merritt-Genore H.M., Siddique A., Miles C.D., Plumb T.J.; Zero balance ultrafiltration using dialysate during nationwide bicarbonate shortage: A retrospective analysis, Journal of Cardiothoracic Surgery
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication– 3rd Quarter 2019
Oncology
Ganti A.K., Wang X., Stinchcombe T.E., Wang Y., Bradley J., Cohen H.J., Kelly K., Paulus R., Ramalingam S.S., Vokes E.E., Pang H.; Clinical prognostic model for older patients with advanced non-small cell lung cancer Journal of Geriatric Oncology
Pulmonary, Critical Care, Sleep and Allergy
Bailey K.L., Smith L.M., Heires A.J., Katafiasz D.M., Romberger D.J., LeVan T.D.; Aging leads to dysfunctional innate immune responses to TLR2 and TLR4 agonists, Aging Clinical and Experimental Research
Rheumatology
England B.R., Duryee M.J., Roul P., Mahajan T.D., Singh N., Poole J.A., Ascherman D.P., Caplan L., Demoruelle M.K., Deane K.D., Klassen L.W., Thiele G.M., Mikuls T.R.; Malondialdehyde–Acetaldehyde Adducts and Antibody Responses in Rheumatoid Arthritis–Associated Interstitial Lung Disease, Arthritis and Rheumatology
Notable Publications - 2nd Quarter 2019
Cardiology
Gastroenterology
General Internal Medicine
Infectious Diseases
Oncology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology
Cardiology
Mathias W., Jr., Tsutsui J.M., Tavares B.G., Fava A.M., Aguiar M.O.D., Borges B.C., Oliveira MT, Jr., Soeiro A., Nicolau J.C., Ribeiro H.B., Chiang H.P., Sbano J.C.N., Morad A., Goldsweig A., Rochitte C.E., Lopes B.B.C., Ramirez J.A.F., Kalil Filho R., Porter T.R., MRUSMI Investigators.,
Sonothrombolysis in ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention, Journal of the American College of Cardiology
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter - 2nd Quarter 2019
Selim A.M., Wadhwani L., Burdorf A., Raichlin E., Lowes B., Zolty R., Left Ventricular Assist Devices in Pulmonary Hypertension Group 2 With Significantly Elevated Pulmonary Vascular Resistance: A Bridge to Cure, Heart, Lung and Circulation
Gastroenterology
Manatsathit W., Samant H., Panjawatanan P., Braseth A., Suh J., Esmadi M., Wiedel N., Ingviya T., Performance of ultrasound for detection of transjugular intrahepatic portosystemic shunt dysfunction: a meta-analysis; Abdominal Radiology
Rasineni K., Thomes P.G., Kubik J.L., Harris E.N., Kharbanda K.K., Casey C.A.; Chronic alcohol exposure alters circulating insulin and ghrelin levels: Role of ghrelin in hepatic steatosis, American Journal of Physiology - Gastrointestinal and Liver Physiology
Thomes P.G., Rasineni K., Yang L., Donohue T.M., Jr, Kubik J.L., McNiven M.A., Casey C.A.; Ethanol withdrawal mitigates fatty liver by normalizing lipid catabolism, American Journal of Physiology - Gastrointestinal and Liver Physiology
Gupta N., Singh S., Vargas L., Moore T.E., Shostrom V.K., Boerner B.P.; Prevalence of Low Bone Density and Comorbid Hypogonadism in Patients with Chronic Pancreatitis, Pancreas
Ganesan M., Poluektova L.Y., Kharbanda K.K., Osna N.A.; Human immunodeficiency virus and hepatotropic viruses comorbidities as the inducers of liver injury progression, World Journal of Gastroenterology
General Internal Medicine
Malik S., Malik S.A., Ulmer L.L., Jha L.K., Strupp MS, Raichlin E., Lyden E.R., Hewlett A.T.; Gastrointestinal bleeding with left ventricular assist devices (LVAD): Locating the leak and identifying outcomes, Journal of Clinical Gastroenterology
Infectious Diseases
Florescu D.F., Schaenman J.M., Adenovirus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice, Clinical Transplantation
Marcelin J.R., Brewer C., Beachy M., Lyden E., Winterboer T., Murphy C.N., Fey P.D., Hood L., Van Schooneveld T.C.; Hardwiring diagnostic stewardship using electronic ordering restrictions for gastrointestinal pathogen testing, Infection Control and Hospital Epidemiology
Schreier T., Sherer R., Sayles H., Jacobsen D.M., Swindells S., Bares S.H.; US Human Immunodeficiency Virus (HIV) practitioners' recommendations regarding condomless sex in the era of HIV pre-exposure prophylaxis and treatment as prevention, Open Forum Infectious Diseases
Cawcutt K.A., Erdahl L.M., Englander M.J., Radford D.M., Oxentenko A.S., Girgis L., Migliore L.L., Poorman J.A., Silver J.K.; Use of a Coordinated Social Media Strategy to Improve Dissemination of Research and Collect Solutions Related to Workforce Gender Equity, Journal of Women's Health
Oncology
Zima L.A., Tulpule S., Samson K., Shonka N.; Seizure prevalence, contributing factors, and prognostic factors in patients with leptomeningeal disease, Journal of the Neurological Sciences
Vengoji R., Macha M.A., Nimmakayala R.K., Rachagani S., Siddiqui J.A., Mallya K., Gorantla S., Jain M., Ponnusamy M.P., Batra S.K., Shonka N.; Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells, Journal of Experimental and Clinical Cancer Research
Teply B.A., Qiu F., Antonarakis E.S., Carducci M.A., Denmeade S.R.; Risk of development of visceral metastases subsequent to abiraterone vs placebo: An analysis of mode of radiographic progression in COU-AA-302, The Prostate
Haney S.L., Varney M.L., Chhonker Y.S., Shin S., Mehla K., Crawford A.J., Smith H.J., Smith L.M., Murry D.J., Hollingsworth M.A., Holstein S.A.; Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma, Oncogene
Pulmonary, Critical Care, Sleep and Allergy
Wyatt T.A., Bailey K.L., Simet S.M., Warren K.J., Sweeter J.M., DeVasure J.M., Pavlik J.A., Sisson J.H.; Alcohol potentiates RSV-mediated injury to ciliated airway epithelium, Alcohol
Rheumatology
Ozen G., Pedro S., Wolfe F., Michaud K.; Medications associated with fracture risk in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication– 2nd Quarter 2019
Ozen G., Pedro S., Schumacher R., Simon T.A., Michaud K.; Safety of abatacept compared with other biologic and conventional synthetic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: Data from an observational study, Arthritis Research and Therapy
Mehta B., Pedro S., Ozen G., Kalil A., Wolfe F., Mikuls T., Michaud K.; Serious infection risk in rheumatoid arthritis compared with non-inflammatory rheumatic and musculoskeletal diseases: A US national cohort study, RMD Open
Notable Publications - 1st Quarter 2019
Cardiology
Gastroenterology
General Internal Medicine
Infectious Diseases
Oncology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology
Cardiology
Goldsweig, A.M., Kennedy, K.F., Abbott, J.D., Jones, W.S., Velagapudi, P., Rutar, F.J., Curtis, J.C., Tsai, T.T., Aronow, H.D.,
Patient Radiation Dosage During Lower Extremity Endovascular Intervention,
JACC: Cardiovascular Interventions
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication - 1st Quarter 2019
Duan, B., Xu, C., Das, S., Chen, J.M., Butcher, J.T., Spatial Regulation of Valve Interstitial Cell Phenotypes within Three-Dimensional Micropatterned Hydrogels, ACS Biomaterials Science and Engineering
Gastroenterology
Rasineni, K., Thomes, P.G., Kubik, J.L., Harris, E.N., Kharbanda, K.K., Casey, C.A., Chronic alcohol exposure alters circulating insulin and ghrelin levels: role of ghrelin in hepatic steatosis, American journal of physiology - Gastrointestinal and liver physiology
General Internal Medicine
Fung, K.W., Xu, J., Rosenbloom, S.T., Campbell, J.R., Using SNOMED CT-encoded problems to improve ICD-10-CM coding—A randomized controlled experiment, International Journal of Medical Informatics
Infectious Diseases
Swindells, S., Ramchandani, R., Gupta, A., Benson, C.A., Leon-Cruz, J., Mwelase, N., Jean Juste, M.A., Lama, J.R., Valencia, J., Omoz-Oarhe, A., Supparatpinyo, K., Masheto, G., Mohapi, L., Da Silva Escada, R.O., Mawlana, S., Banda, P., Severe, P., Hakim, J., Kanyama, C., Langat, D., Moran, L., Andersen, J., Fletcher, C.V., Nuermberger, E., Chaisson, R.E., One month of rifapentine plus isoniazid to prevent HIV-related Tuberculosis, New England Journal of Medicine
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 1st Quarter 2019
Hewlett, A.L., Hohenberger, H., Murphy, C.N., Helget, L., Hausmann, H., Lyden, E., Fey, P.D., Hicks, R., Evaluation of the bacterial burden of gel nails, standard nail polish, and natural nails on the hands of health care workers, Am J Infect Control (Article is in German)
Oncology
Ernani, V., Appiah, A. K., Marr, A., Zhang, C., Zhen, W., Smith, L. M., & Ganti, A. K., Adjuvant Systemic Therapy in Patients With Early-Stage NSCLC Treated With Stereotactic Body Radiation Therapy. Journal of Thoracic Oncology
Ganti, A.K., Wang, X., Stinchcombe, T.E., Wang, Y., Bradley, J., Cohen, H.J., Kelly, K., Paulus, R., Ramalingam, S.S., Vokes, E.E., Pang, H., Clinical prognostic model for older patients with advanced non-small cell lung cancer, Journal of Geriatric Oncology
Haney, S.L., Varney, M.L., Safranek, H.R., Chhonker, Y.S., G-Dayanandan, N., Talmon, G., Murry, D.J., Wiemer, A.J., Wright, D.L., Holstein, S.A., Tropolone-induced effects on the unfolded protein response pathway and apoptosis in multiple myeloma cells are dependent on iron, Leukemia Research
Pulmonary, Critical Care, Sleep and Allergy
Poole, J.A., Barnes, C.S., Demain, J.G., Bernstein, J.A., Padukudru, M.A., Sheehan, W.J., Fogelbach, G.G., Wedner, J., Codina, R., Levetin, E., Cohn, J.R., Kagen, S., Portnoy, J.M., Nel, A.E., Impact of weather and climate change with indoor and outdoor air quality in asthmatic patients, Journal of Allergy and Clinical Immunology
Nordgren, T.M., Heires, A.J., Zempleni, J., Swanson, B.J., Wichman, C., Romberger, D.J., Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice, Journal of Nutritional Biochemistry
Warren, K.J., Dickinson, J.D., Nelson, A.J., Wyatt, T.A., Romberger, D.J., Poole, J.A., Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust, Respiratory Research
Dickinson, J.D., Sweeter, J.M., Staab, E.B., Nelson, A.J., Bailey, K.L., Warren, K.J., Jaramillo, A.M., Dickey, B.F., Poole, J.A., Myd88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultural organic dust exposure, American Journal of Physiology - Lung Cellular and Molecular Physiology
Rheumatology
Maloley, P.M., England, B.R., Sayles, H., Thiele, G.M., Michaud, K., Sokolove, J., Cannon, G.W., Reimold, A.M., Kerr, G.S., Baker, J.F., Caplan, L., Case, A.J., Mikuls, T.R., Post-traumatic stress disorder and serum cytokine and chemokine concentrations in patients with rheumatoid arthritis, Seminars in Arthritis and Rheumatism
Mikuls, T.R., Cheetham, T.C., Levy, G.D., Rashid, N., Kerimian, A., Low, K.J., Coburn, B.W., Redden, D.T., Saag, K.G., Foster, P.J., Chen, L., R. Curtis, J., Adherence and Outcomes with Urate-Lowering Therapy: A Site-Randomized Trial, American Journal of Medicine
Notable Publications - 4th Quarter 2018
Diabetes, Endocrinology, and Metabolism
Gastroenterology
General Medicine
Infectious Diseases
Oncology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology
Diabetes, Endocrinology, and Metabolism
Drincic, A., Nguyen, A. T., Singh, S., Zena, M., Walters, R., Friedman, K., & Anderson, R. J. Pituitary evaluation in patients with low prostate-specific antigen. Endocrine Practice
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 4th Quarter 2018
Gastroenterology
Casey, C. A., Thomes, P., Manca, S., & Petrosyan, A, Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells, Biomolecules
Ganesan, M., Poluektova, L. Y., Enweluzo, C., Kharbanda, K. K., & Osna, N. A., Hepatitis C virus-infected apoptotic hepatocytes program macrophages and hepatic stellate cells for liver inflammation and fibrosis development: Role of ethanol as a second hit, Biomolecules
General Medicine
Smith, C. J., Matthias, T., Beam, E., Wampler, K., Pounds, L., Nickol, D., Carlson, K., & Michael, K., Building a Bigger Tent in Point-Of-Care Ultrasound Education: A Mixed-Methods evaluation of Interprofessional, Near-Peer Teaching of Internal Medicine Residents by Sonography Students, BMC Medical Education
Infectious Diseases
Broekhuis, J. M., Scarsi, K. K., Sayles, H. R., Klepser, D. G., Havens, J. P., Swindells, S., & Bares, S. H., Midwest Pharmacists' Familiarity, Experience, and Willingness to Provide Pre-Exposure Prophylaxis (PrEP) for HIV, PLoS One
Majorant, D., Qiu, F., Kalil, A. C., Wilson, N., & Florescu, D. F., Adenovirus—A Deadly Disease in the Solid Organ Transplant Population: Risk Factors and Outcomes, Transplantation Proceedings
Oncology
Ernani, V., Appiah, A. K., Marr, A., Zhang, C., Zhen, W., Smith, L. M., & Ganti, A. K., Adjuvant Systemic Therapy in Patients With Early-Stage NSCLC Treated With Stereotactic Body Radiation Therapy. Journal of Thoracic Oncology
Umakanthan, J. M., Iqbal, J., Batlevi, C. L., Bouska, A., Smith, L. M., Shostrom, V., Nutsch, H., William, B. M., Gregory Bociek, R., Lunning, M., Bierman, P., Younes, A., Armitage, J. O., & Vose, J. M., Phase I/II study of dasatinib and exploratory genomic analysis in relapsed or refractory non-Hodgkin lymphoma, British Journal of Haematology
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 4th Quarter 2018
Pulmonary, Critical Care, Sleep and Allergy
Bailey, K. L., Kharbanda, K. K., Katafiasz, D. M., Sisson, J. H., & Wyatt, T. A, Oxidative stress associated with aging activates protein kinase Cε, leading to cilia slowing, American Journal of Physiology - Lung Cellular and Molecular Physiology
Rheumatology
Mikuls, T. R., Cheetham, T. C., Levy, G. D., Rashid, N., Kerimian, A., Low, K. J., Coburn, B. W., Redden, D. T., Saag, K. G., Foster, P. J., Chen, L., & R. Curtis, J. Adherence and Outcomes with Urate-Lowering Therapy: A Site-Randomized Trial, American Journal of Medicine
England, B. R., Sayles, H., Michaud, K., Thiele, G. M., Poole, J. A., Caplan, L., Sauer, B. C., Cannon, G. W., Reimold, A., Kerr, G. S., Baker, J. F., & Mikuls, T. R., Chronic lung disease in U.S. Veterans with rheumatoid arthritis and the impact on survival, Clinical Rheumatology
Notable Publications - 3rd Quarter 2018
Cardiovascular MedicineGeneral Medicine
Infectious Diseases
Nephrology
Pulmonary, Critical Care, Sleep and Allergy
Cardiovascular Medicine
Ying Wang; Sameer Mirza; Shaohua Wu; Jiping Zeng; Wen Shi; Hamid Band; Vimla Band; Bin Duan, 3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition, Oncotarget
Dianjun Qi; Shaohua Wu; Mitchell A. Kuss; Wen Shi; Soonkyu Chung; Paul T. Deegan; Alexey Kamenskiy; Yini He; Bin Duan, Mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, Acta Biomaterialia
General Medicine
Jason F. Shiffermiller, MD, MPH , Benjamin J. Monson, MD, Chad W. Vokoun, MD, Micah W. Beachy, DO, Michael P. Smith, MD, James N. Sullivan, MD, Andrew J. Vasey, MD,Purnima Guda, PhD, Elizabeth R. Lyden, MS, Sheila J. Ellis, MD, Huiling Pang, MD PhD, Rachel E. Thompson, MD, MPH, Prospective Randomized Evaluation of Preoperative Angiotensin-Converting Enzyme Inhibition (PREOP-ACEI), Journal of Hospital Medicine
*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 3rd Quarter 2018
Infectious Diseases
Hewlett A.L., Hohenberger H., Murphy C.N., Helget L., Hausmann H., Lyden E., Fey P.D., Hicks R., Evaluation of the bacterial burden of gel nails, standard nail polish, and natural nails on the hands of health care workers, American Journal of Infection Control
Bares S.H., Smeaton L.M., Xu A., Godfrey C., McComsey G.A., HIV-Infected Women Gain More Weight than HIV-Infected Men Following the Initiation of Antiretroviral Therapy, Journal of Women's Health
Nephrology
Florescu M.C., Runge J., Flora M., Nio G., Lof J., Stolze E., Fry G., Radio S.J., Foster K.W., Location and structure of fibrous sheath formed after placing a tunneled hemodialysis catheter in a large pig model, Journal of Vascular Access
Pulmonary, Critical Care, Sleep and Allergy
Tricia D. LeVan; Debra J. Romberger; Mohammad Siahpush; Brandon L. Grimm; Athena K. Ramos; Patrik L. Johansson; Tzeyu L. Michaud; Art J. Heires; Todd A. Wyatt; Jill A. Poole, Relationship of systemic IL-10 levels with proinflammatory cytokine responsiveness and lung function in agriculture workers, Respiratory Research
Price M.E., Case A.J., Pavlik J.A., Devasure J.M., Wyatt T.A., Zimmerman M.C., Sisson J.H., S-nitrosation of protein phosphatase 1 mediates alcohol-induced ciliary dysfunction, Scientific Reports
Notable Publications - 1st and 2nd Quarter 2018
Cardiovascular MedicineGastroenterology and Hepatology
General Medicine
Infectious Diseases
Oncology and Hematology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology and Immunology
Cardiovascular Medicine
Lundgren S., Poon C.Y.M., Selim A., Lowes B.D., Zolty R., Burdorf A., Potashnik-Peled Y., Moulton M.J., Um J.Y., Raichlin E., Depression and anxiety in patients undergoing left ventricular assist device implantation, International Journal of Artificial Organs
Kuss M., Kim J., Qi D., Wu S., Lei Y., Chung S., Duan B., Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function, Acta Biomaterialia,
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 1st and 2nd Quarter 2018
Schleifer J.W., Pislaru S.V., Lin G., Powell B.D., Espinosa R., Koestler C., Thome T., Polk L., Li Z., Asirvatham S.J., Cha Y.-M., Effect of ventricular pacing lead position on tricuspid regurgitation: A randomized prospective trial, Heart Rhythm
Schleifer J.W., Manocha K.K., Asirvatham S.J., Noseworthy PA, Gulati R., Friedman PA, Madhavan M., Munger T.M., Cooper L.T., Reeder G.S., Holmes D.R., Jr., Kapa S., Feasibility of Performing Radiofrequency Catheter Ablation and Endomyocardial Biopsy in the Same Setting, American Journal of Cardiology
Abdulsalam N., Goldsweig A.M., Porous CARDIOFORM Septal Occluder Balloons Within the Right Atrial Cavity, JACC: Cardiovascular Interventions
Aggarwal S., Xie F., High R., Pavlides G., Porter T.R., Prevalence and Predictive Value of Microvascular Flow Abnormalities after Successful Contemporary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction, Journal of the American Society of Echocardiography
Gastroenterology and Hepatology
Murali Ganesan; Raghubendra Singh Dagur; Edward Makarov; Larisa I. Poluektova; Srivatsan Kidambi; Natalia A. Osna, Matrix stiffness regulate apoptotic cell death in HIV-HCV co-infected hepatocytes, Biochemical and Biophysical Research Communications
General Medicine
Campbell W.S., Karlsson D., Vreeman D.J., Lazenby A.J., Talmon G.A., Campbell J.R., A computable pathology report for precision medicine: Extending an observables ontology unifying SNOMED CT and LOINC, Journal of the American Medical Informatics Association
Derrick Antoniak; Chandrakanth Are; Chad Vokoun; Kaeli Samson; Lynette Smith; Jason Shiffermiller, The Relationship Between Age and Chronic Kidney Disease in Patients Undergoing Pancreatic Resection, Journal of Gastrointestinal Surgery,
Infectious Diseases
Kalil A.C., Gilbert D.N., Winslow D.L., Masur H., Klompas M., Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines, Clinical Infectious Diseases
Oncology and Hematology
Gale R.P., Armitage J.O., Are we prepared for nuclear terrorism?, New England Journal of Medicine
Teply B.A., Wang H., Luber B., Sullivan R., Rifkind I., Bruns A., Spitz A., DeCarli M., Sinibaldi V., Pratz C.F., Lu C., Silberstein J.L., Luo J., Schweizer MT, Drake C.G., Carducci M.A., Paller C.J., Antonarakis E.S., Eisenberger M.A., Denmeade S.R., Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study, The Lancet Oncology
Holstein S.A., Avet-Loiseau H., Hahn T., Ho C.M., Lohr J.G., Munshi N.C., Paiva B., Pasquini M.C., Tario J.D., Usmani S.Z., Wallace P.K., Weisel K., McCarthy P.L., BMT CTN Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling: Summary and Recommendations from the Organizing Committee, Biology of Blood and Marrow Transplantation
Haney S.L., Chhonker Y.S., Varney M.L., Talmon G., Murry D.J., Holstein S.A., Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor, Investigational New Drugs
Bhatt V.R., Chen B., Gyawali B., Lee S.J., Socioeconomic and health system factors associated with lower utilization of hematopoietic cell transplantation in older patients with acute myeloid leukemia, Bone Marrow Transplantation
* Selected as the UNMC Department of Internal Medicine Publication of the Quarter - 1st and 2nd Quarter 2018
Pulmonary, Critical Care, Sleep and Allergy
Tara M. Nordgren; Kristina L. Bailey; Art J. Heires; Dawn Katafiasz; Debra J. Romberger, Effects of agricultural organic dusts on human lung-resident mesenchymal stem (Stromal) cell function, Toxicological Sciences
Sinha R., Weissenburger-Moser L.A., Clarke J.L., Smith L.M., Heires A.J., Romberger D.J., LeVan T.D., Short term dynamics of the sputum microbiome among COPD patients, PLoS ONE
Rheumatology and Immunology
Bryant R. England; Joshua F. Baker; Harlan Sayles; Kaleb Michaud; Liron Caplan; Lisa A. Davis; Grant W. Cannon; Brian C. Sauer; E. Blair Solow; Andreas M. Reimold; Gail S. Kerr; Ted R. Mikuls, Body Mass Index, Weight Loss, and Cause-Specific Mortality in Rheumatoid Arthritis, Arthritis Care and Research
Duryee M.J., Wiese B.M., Bowman J.R., Vanlandingham J.D., Klassen L.W., Thiele G.E., Hunter C.D., Anderson D.R., Mikuls T.R., Thiele G.M., Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation, American Journal of Physiology - Gastrointestinal and Liver Physiology,
*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 1st and 2nd Quarter 2018
Khadge S., Thiele G.M., Sharp J.G., McGuire T.R., Klassen L.W., Black P.N., DiRusso C.C., Talmadge J.E., Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation, Journal of Mammary Gland Biology and Neoplasia
Mikuls T.R., Duryee M.J., England B.R., Anderson D.R., Hearth-Holmes M., Su K., Michaud K., Payne J.B., Sayles H., Hunter C., McGowan J.D., Klassen L.W., Thiele G.M., Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions, International Immunopharmacology
Gulsen Ozen; Diane L. Kamen; Ted R. Mikuls; Bryant R. England; Frederick Wolfe; Kaleb Michaud, Trends and Determinants of Osteoporosis Treatment and Screening in Patients With Rheumatoid Arthritis Compared to Osteoarthritis, Arthritis Care and Research
Notable Publications - 4th Quarter 2017
Cardiovascular MedicineDiabetes, Endocrine & Metabolism
Gastroenterology and Hepatology
Infectious Diseases
Oncology and Hematology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology and Immunology
Cardiovascular Medicine
Chatzizisis Y.S., Toutouzas K., Giannopoulos A.A., Riga M., Antoniadis A.P., Fujinom Y., Mitsouras D., Koutkias V.G., Cheimariotis G., Doulaverakis C., Tsampoulatidis I., Chouvarda I., Kompatsiaris I., Nakamura S., Rybicki F.J., Maglaveras N., Tousoulis D., Giannoglou G.D.
Association of global and local low endothelial shear stress with high-risk plaque using intracoronary 3D optical coherence tomography: Introduction of 'shear stress score
European Heart Journal Cardiovascular Imaging
Wu S., Peng H., Li X., Streubel P.N., Liu Y., Duan B.
Effect of scaffold morphology and cell co-culture on tenogenic differentiation of HADMSC on centrifugal melt electrospun poly (L-lactic acid) fibrous meshes
Biofabrication
Wu S., Wang Y., Streubel P.N., Duan B.
Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation
Acta Biomaterialia
*Selected as the UNMC Department of Internal Medicine Publication of the Quarter – 4 th Quarter 2017
Aggarwal S, Xie F, Porter TR
Masking and Unmasking of Isolated Noncompaction of the Left Ventricle With Real-Time Contrast Echocardiography
Circ Cardiovasc Imaging
Kuss M.A., Wu S., Wang Y., Untrauer J.B., Li W., Lim J.Y., Duan B.
Prevascularization of 3D printed bone scaffolds by bioactive hydrogels and cell co-culture
Journal of Biomedical Materials Research - Part B Applied Biomaterials
Goldsweig A.M., Kennedy K.F., Kolte D., Abbott J.D., Gordon P.C., Sharaf B.L., Sellke F.W., Ehsan A., Sodha N.R., Rutar F., Aronow H.D.
Predictors of patient radiation exposure during transcatheter aortic valve replacement
Catheterization and Cardiovascular Interventions
Diabetes, Endocrine & Metabolism
Gopalakrishnan Natarajan; Curtis Perriotte-Olson; Fatema Bhinderwala; Robert Powers; Cyrus V. Desouza; Geoffrey A. Talmon; Jiang Yuhang; Matthew C. Zimmerman; Alexander V. Kabanov; Viswanathan Saraswathi
Nanoformulated copper/zinc superoxide dismutase exerts differential effects on glucose vs lipid homeostasis depending on the diet composition possibly via altered AMPK signaling
Translational Research
Gastroenterology and Hepatology
Burchett K.M., Etekpo A., Batra S.K., Yan Y., Ouellette M.M.
Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells
Oncotarget
*Selected as the UNMC Department of Internal Medicine Honorable Mention Publication – 4 th Quarter 2017
Infectious Diseases
Jones R.L., Sayles H.R., Fey P.D., Rupp M.E.
Effect of Clinical Variables on the Volume of Blood Collected for Blood Cultures in an Adult Patient Population
Infection Control and Hospital Epidemiology
Oncology and Hematology
Michael Baine; Tim Dorius; Nathan Bennion; Morshed Alam; Lynette Smith; Weining Zhen; Apar Ganti
Chemoradiotherapy for locally advanced squamous cell carcinoma of the oropharynx
Oral Oncology
Haney S.L., Allen C., Varney M.L., Dykstra K.M., Falcone E.R., Colligan S.H., Hu Q., Aldridge A.M., Wright D.L., Wiemer A.J., Holstein S.A.
Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells
Oncotarget
Baine M.J., Dorius T., Bennion N., Smith L., Zhen W., Ganti A.K.
Weight loss and percutaneous endoscopic gastrostomy tube placement during chemoradiotherapy for locally advanced cancer of the oropharynx do not negatively impact outcomes
Frontiers in Oncology
Pulmonary, Critical Care, Sleep and Allergy
Poole J.A., Mikuls T.R., Duryee M.J., Warren K.J., Wyatt T.A., Nelson A.J., Romberger D.J., West W.W., Thiele G.M.
A role for B cells in organic dust induced lung inflammation
Respiratory Research
Sapkota M., Burnham E.L., DeVasure J.M., Sweeter J.M., Hunter C.D., Duryee M.J., Klassen L.W., Kharbanda K.K., Sisson J.H., Thiele G.M., Wyatt T.A.
Malondialdehyde–Acetaldehyde (MAA) Protein Adducts Are Found Exclusively in the Lungs of Smokers with Alcohol Use Disorders and Are Associated with Systemic Anti-MAA Antibodies
Alcoholism: Clinical and Experimental Research
Hanson C., Lyden E., Weissenburger-Moser L., Furtado J., Romberger D.J., LeVan T.D.
Serum level of nutritional antioxidants are decreased in veteran smokers with COPD
Journal of Military and Veterans' Health
Rheumatology and Immunology
Mikuls T.R., Duryee M.J., Rahman R., Anderson D.R., Sayles H.R., Hollins A., Michaud K., Wolfe F., Thiele G.E., Sokolove J., Robinson W.H., Lingampalli N., Nicholas A.P., Talmon G.A., Su K., Zimmerman M.C., Klassen L.W., Thiele G.M.
Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint
Rheumatology (Oxford, England)
Bryant R. England; Ted R. Mikuls; Fenglong Xie; Shuo Yang; Lang Chen; Jeffrey R. Curtis
Herpes Zoster as a Risk Factor for Incident Giant Cell Arteritis
Arthritis and Rheumatology
Peper S.M., Lew R., Mikuls T., Brophy M., Rybin D., Wu H., O'Dell J.
Rheumatoid Arthritis Treatment After Methotrexate: The Durability of Triple Therapy Versus Etanercept
Arthritis Care and Research