Notable Publications - 4th Quarter 2018

Diabetes, Endocrinology, and Metabolism
Gastroenterology
General Medicine
Infectious Diseases
Oncology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology

Diabetes, Endocrinology, and Metabolism

Drincic, A., Nguyen, A. T., Singh, S., Zena, M., Walters, R., Friedman, K., & Anderson, R. J.  Pituitary evaluation in patients with low prostate-specific antigen. Endocrine Practice

*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 4th Quarter 2018

Gastroenterology

Casey, C. A., Thomes, P., Manca, S., & Petrosyan, A, Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells, Biomolecules

Ganesan, M., Poluektova, L. Y., Enweluzo, C., Kharbanda, K. K., & Osna, N. A.,  Hepatitis C virus-infected apoptotic hepatocytes program macrophages and hepatic stellate cells for liver inflammation and fibrosis development: Role of ethanol as a second hit, Biomolecules

General Medicine

Smith, C. J., Matthias, T., Beam, E., Wampler, K., Pounds, L., Nickol, D., Carlson, K., & Michael, K., Building a Bigger Tent in Point-Of-Care Ultrasound Education: A Mixed-Methods evaluation of Interprofessional, Near-Peer Teaching of Internal Medicine Residents by Sonography Students, BMC Medical Education

Infectious Diseases

Broekhuis, J. M., Scarsi, K. K., Sayles, H. R., Klepser, D. G., Havens, J. P., Swindells, S., & Bares, S. H., Midwest Pharmacists' Familiarity, Experience, and Willingness to Provide Pre-Exposure Prophylaxis (PrEP) for HIV, PLoS One

Majorant, D., Qiu, F., Kalil, A. C., Wilson, N., & Florescu, D. F., Adenovirus—A Deadly Disease in the Solid Organ Transplant Population: Risk Factors and Outcomes, Transplantation Proceedings

Oncology

Ernani, V., Appiah, A. K., Marr, A., Zhang, C., Zhen, W., Smith, L. M., & Ganti, A. K.,  Adjuvant Systemic Therapy in Patients With Early-Stage NSCLC Treated With Stereotactic Body Radiation Therapy. Journal of Thoracic Oncology

Umakanthan, J. M., Iqbal, J., Batlevi, C. L., Bouska, A., Smith, L. M., Shostrom, V., Nutsch, H., William, B. M., Gregory Bociek, R., Lunning, M., Bierman, P., Younes, A., Armitage, J. O., & Vose, J. M., Phase I/II study of dasatinib and exploratory genomic analysis in relapsed or refractory non-Hodgkin lymphoma, British Journal of Haematology

*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 4th Quarter 2018

Pulmonary, Critical Care, Sleep and Allergy

Bailey, K. L., Kharbanda, K. K., Katafiasz, D. M., Sisson, J. H., & Wyatt, T. A, Oxidative stress associated with aging activates protein kinase Cε, leading to cilia slowing, American Journal of Physiology - Lung Cellular and Molecular Physiology

Rheumatology

Mikuls, T. R., Cheetham, T. C., Levy, G. D., Rashid, N., Kerimian, A., Low, K. J., Coburn, B. W., Redden, D. T., Saag, K. G., Foster, P. J., Chen, L., & R. Curtis, J. Adherence and Outcomes with Urate-Lowering Therapy: A Site-Randomized Trial, American Journal of Medicine

England, B. R., Sayles, H., Michaud, K., Thiele, G. M., Poole, J. A., Caplan, L., Sauer, B. C., Cannon, G. W., Reimold, A., Kerr, G. S., Baker, J. F., & Mikuls, T. R., Chronic lung disease in U.S. Veterans with rheumatoid arthritis and the impact on survival, Clinical Rheumatology

Notable Publications - 3rd Quarter 2018

Cardiovascular Medicine

Ying Wang; Sameer Mirza; Shaohua Wu; Jiping Zeng; Wen Shi; Hamid Band; Vimla Band; Bin Duan, 3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition, Oncotarget

Dianjun Qi; Shaohua Wu; Mitchell A. Kuss; Wen Shi; Soonkyu Chung; Paul T. Deegan; Alexey Kamenskiy; Yini He; Bin Duan, Mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, Acta Biomaterialia

General Medicine

Jason F. Shiffermiller, MD, MPH , Benjamin J. Monson, MD, Chad W. Vokoun, MD, Micah W. Beachy, DO, Michael P. Smith, MD, James N. Sullivan, MD, Andrew J. Vasey, MD,Purnima Guda, PhD, Elizabeth R. Lyden, MS, Sheila J. Ellis, MD, Huiling Pang, MD PhD, Rachel E. Thompson, MD, MPH, Prospective Randomized Evaluation of Preoperative Angiotensin-Converting Enzyme Inhibition (PREOP-ACEI), Journal of Hospital Medicine

*Selected as a UNMC Department of Internal Medicine Publication of the Quarter – 3rd Quarter 2018

Infectious Diseases

Hewlett A.L., Hohenberger H., Murphy C.N., Helget L., Hausmann H., Lyden E., Fey P.D., Hicks R., Evaluation of the bacterial burden of gel nails, standard nail polish, and natural nails on the hands of health care workers, American Journal of Infection Control

Bares S.H., Smeaton L.M., Xu A., Godfrey C., McComsey G.A., HIV-Infected Women Gain More Weight than HIV-Infected Men Following the Initiation of Antiretroviral Therapy, Journal of Women's Health

Nephrology

Florescu M.C., Runge J., Flora M., Nio G., Lof J., Stolze E., Fry G., Radio S.J., Foster K.W., Location and structure of fibrous sheath formed after placing a tunneled hemodialysis catheter in a large pig model, Journal of Vascular Access

Pulmonary, Critical Care, Sleep and Allergy

Tricia D. LeVan; Debra J. Romberger; Mohammad Siahpush; Brandon L. Grimm; Athena K. Ramos; Patrik L. Johansson; Tzeyu L. Michaud; Art J. Heires; Todd A. Wyatt; Jill A. Poole, Relationship of systemic IL-10 levels with proinflammatory cytokine responsiveness and lung function in agriculture workers, Respiratory Research

Price M.E., Case A.J., Pavlik J.A., Devasure J.M., Wyatt T.A., Zimmerman M.C., Sisson J.H., S-nitrosation of protein phosphatase 1 mediates alcohol-induced ciliary dysfunction, Scientific Reports

Notable Publications - 1st and 2nd Quarter 2018

Cardiovascular Medicine

Lundgren S., Poon C.Y.M., Selim A., Lowes B.D., Zolty R., Burdorf A., Potashnik-Peled Y., Moulton M.J., Um J.Y., Raichlin E., Depression and anxiety in patients undergoing left ventricular assist device implantation, International Journal of Artificial Organs

Kuss M., Kim J., Qi D., Wu S., Lei Y., Chung S., Duan B., Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function, Acta Biomaterialia,

*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 1st and 2nd Quarter 2018

Schleifer J.W., Pislaru S.V., Lin G., Powell B.D., Espinosa R., Koestler C., Thome T., Polk L., Li Z., Asirvatham S.J., Cha Y.-M., Effect of ventricular pacing lead position on tricuspid regurgitation: A randomized prospective trial, Heart Rhythm

Schleifer J.W., Manocha K.K., Asirvatham S.J., Noseworthy P.A., Gulati R., Friedman P.A., Madhavan M., Munger T.M., Cooper L.T., Reeder G.S., Holmes D.R., Jr., Kapa S., Feasibility of Performing Radiofrequency Catheter Ablation and Endomyocardial Biopsy in the Same Setting, American Journal of Cardiology

Abdulsalam N., Goldsweig A.M., Porous CARDIOFORM Septal Occluder Balloons Within the Right Atrial Cavity, JACC: Cardiovascular Interventions

Aggarwal S., Xie F., High R., Pavlides G., Porter T.R., Prevalence and Predictive Value of Microvascular Flow Abnormalities after Successful Contemporary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction, Journal of the American Society of Echocardiography

Gastroenterology and Hepatology

Murali Ganesan; Raghubendra Singh Dagur; Edward Makarov; Larisa I. Poluektova; Srivatsan Kidambi; Natalia A. Osna, Matrix stiffness regulate apoptotic cell death in HIV-HCV co-infected hepatocytes, Biochemical and Biophysical Research Communications

General Medicine

Campbell W.S., Karlsson D., Vreeman D.J., Lazenby A.J., Talmon G.A., Campbell J.R., A computable pathology report for precision medicine: Extending an observables ontology unifying SNOMED CT and LOINC, Journal of the American Medical Informatics Association

Derrick Antoniak; Chandrakanth Are; Chad Vokoun; Kaeli Samson; Lynette Smith; Jason Shiffermiller, The Relationship Between Age and Chronic Kidney Disease in Patients Undergoing Pancreatic Resection, Journal of Gastrointestinal Surgery,

Infectious Diseases

Kalil A.C., Gilbert D.N., Winslow D.L., Masur H., Klompas M., Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines, Clinical Infectious Diseases

Oncology and Hematology

Gale R.P., Armitage J.O., Are we prepared for nuclear terrorism?, New England Journal of Medicine

Teply B.A., Wang H., Luber B., Sullivan R., Rifkind I., Bruns A., Spitz A., DeCarli M., Sinibaldi V., Pratz C.F., Lu C., Silberstein J.L., Luo J., Schweizer M.T., Drake C.G., Carducci M.A., Paller C.J., Antonarakis E.S., Eisenberger M.A., Denmeade S.R., Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study, The Lancet Oncology

Holstein S.A., Avet-Loiseau H., Hahn T., Ho C.M., Lohr J.G., Munshi N.C., Paiva B., Pasquini M.C., Tario J.D., Usmani S.Z., Wallace P.K., Weisel K., McCarthy P.L., BMT CTN Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling: Summary and Recommendations from the Organizing Committee, Biology of Blood and Marrow Transplantation

Haney S.L., Chhonker Y.S., Varney M.L., Talmon G., Murry D.J., Holstein S.A., Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor, Investigational New Drugs

Bhatt V.R., Chen B., Gyawali B., Lee S.J., Socioeconomic and health system factors associated with lower utilization of hematopoietic cell transplantation in older patients with acute myeloid leukemia, Bone Marrow Transplantation

* Selected as the UNMC Department of Internal Medicine Publication of the Quarter - 1st and 2nd Quarter 2018

Pulmonary, Critical Care, Sleep and Allergy

Tara M. Nordgren; Kristina L. Bailey; Art J. Heires; Dawn Katafiasz; Debra J. Romberger, Effects of agricultural organic dusts on human lung-resident mesenchymal stem (Stromal) cell function, Toxicological Sciences

 Sinha R., Weissenburger-Moser L.A., Clarke J.L., Smith L.M., Heires A.J., Romberger D.J., LeVan T.D., Short term dynamics of the sputum microbiome among COPD patients, PLoS ONE

Rheumatology and Immunology

Bryant R. England; Joshua F. Baker; Harlan Sayles; Kaleb Michaud; Liron Caplan; Lisa A. Davis; Grant W. Cannon; Brian C. Sauer; E. Blair Solow; Andreas M. Reimold; Gail S. Kerr; Ted R. Mikuls, Body Mass Index, Weight Loss, and Cause-Specific Mortality in Rheumatoid Arthritis, Arthritis Care and Research

Duryee M.J., Wiese B.M., Bowman J.R., Vanlandingham J.D., Klassen L.W., Thiele G.E., Hunter C.D., Anderson D.R., Mikuls T.R., Thiele G.M., Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation, American Journal of Physiology - Gastrointestinal and Liver Physiology,

*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 1st and 2nd Quarter 2018

Khadge S., Thiele G.M., Sharp J.G., McGuire T.R., Klassen L.W., Black P.N., DiRusso C.C., Talmadge J.E., Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation, Journal of Mammary Gland Biology and Neoplasia

Mikuls T.R., Duryee M.J., England B.R., Anderson D.R., Hearth-Holmes M., Su K., Michaud K., Payne J.B., Sayles H., Hunter C., McGowan J.D., Klassen L.W., Thiele G.M., Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions, International Immunopharmacology

Gulsen Ozen; Diane L. Kamen; Ted R. Mikuls; Bryant R. England; Frederick Wolfe; Kaleb Michaud, Trends and Determinants of Osteoporosis Treatment and Screening in Patients With Rheumatoid Arthritis Compared to Osteoarthritis, Arthritis Care and Research

Notable Publications - 4th Quarter 2017

Cardiovascular Medicine

Chatzizisis Y.S., Toutouzas K., Giannopoulos A.A., Riga M., Antoniadis A.P., Fujinom Y., Mitsouras D., Koutkias V.G., Cheimariotis G., Doulaverakis C., Tsampoulatidis I., Chouvarda I., Kompatsiaris I., Nakamura S., Rybicki F.J., Maglaveras N., Tousoulis D., Giannoglou G.D.
Association of global and local low endothelial shear stress with high-risk plaque using intracoronary 3D optical coherence tomography: Introduction of 'shear stress score
European Heart Journal Cardiovascular Imaging

Wu S., Peng H., Li X., Streubel P.N., Liu Y., Duan B.
Effect of scaffold morphology and cell co-culture on tenogenic differentiation of HADMSC on centrifugal melt electrospun poly (L-lactic acid) fibrous meshes 
Biofabrication

Wu S., Wang Y., Streubel P.N., Duan B.
Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation
Acta Biomaterialia

*Selected as the UNMC Department of Internal Medicine Publication of the Quarter – 4 ^th Quarter 2017 

Aggarwal S, Xie F, Porter TR
Masking and Unmasking of Isolated Noncompaction of the Left Ventricle With Real-Time Contrast Echocardiography
Circ Cardiovasc Imaging

Kuss M.A., Wu S., Wang Y., Untrauer J.B., Li W., Lim J.Y., Duan B.
Prevascularization of 3D printed bone scaffolds by bioactive hydrogels and cell co-culture
Journal of Biomedical Materials Research - Part B Applied Biomaterials

Goldsweig A.M., Kennedy K.F., Kolte D., Abbott J.D., Gordon P.C., Sharaf B.L., Sellke F.W., Ehsan A., Sodha N.R., Rutar F., Aronow H.D.
Predictors of patient radiation exposure during transcatheter aortic valve replacement
Catheterization and Cardiovascular Interventions 

Diabetes, Endocrine & Metabolism

Gopalakrishnan Natarajan; Curtis Perriotte-Olson; Fatema Bhinderwala; Robert Powers; Cyrus V. Desouza; Geoffrey A. Talmon; Jiang Yuhang; Matthew C. Zimmerman; Alexander V. Kabanov; Viswanathan Saraswathi
Nanoformulated copper/zinc superoxide dismutase exerts differential effects on glucose vs lipid homeostasis depending on the diet composition possibly via altered AMPK signaling
Translational Research 

Gastroenterology and Hepatology

Burchett K.M., Etekpo A., Batra S.K., Yan Y., Ouellette M.M.
Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells
Oncotarget 

*Selected as the UNMC Department of Internal Medicine Honorable Mention Publication – 4 ^th Quarter 2017

Infectious Diseases

Jones R.L., Sayles H.R., Fey P.D., Rupp M.E.
Effect of Clinical Variables on the Volume of Blood Collected for Blood Cultures in an Adult Patient Population
Infection Control and Hospital Epidemiology 

Oncology and Hematology

Michael Baine; Tim Dorius; Nathan Bennion; Morshed Alam; Lynette Smith; Weining Zhen; Apar Ganti
Chemoradiotherapy for locally advanced squamous cell carcinoma of the oropharynx
Oral Oncology 

Haney S.L., Allen C., Varney M.L., Dykstra K.M., Falcone E.R., Colligan S.H., Hu Q., Aldridge A.M., Wright D.L., Wiemer A.J., Holstein S.A.
Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells
Oncotarget

Baine M.J., Dorius T., Bennion N., Smith L., Zhen W., Ganti A.K.
Weight loss and percutaneous endoscopic gastrostomy tube placement during chemoradiotherapy for locally advanced cancer of the oropharynx do not negatively impact outcomes
Frontiers in Oncology

Pulmonary, Critical Care, Sleep and Allergy

Poole J.A., Mikuls T.R., Duryee M.J., Warren K.J., Wyatt T.A., Nelson A.J., Romberger D.J., West W.W., Thiele G.M.
A role for B cells in organic dust induced lung inflammation
Respiratory Research

Sapkota M., Burnham E.L., DeVasure J.M., Sweeter J.M., Hunter C.D., Duryee M.J., Klassen L.W., Kharbanda K.K., Sisson J.H., Thiele G.M., Wyatt T.A.
Malondialdehyde–Acetaldehyde (MAA) Protein Adducts Are Found Exclusively in the Lungs of Smokers with Alcohol Use Disorders and Are Associated with Systemic Anti-MAA Antibodies
Alcoholism: Clinical and Experimental Research

Hanson C., Lyden E., Weissenburger-Moser L., Furtado J., Romberger D.J., LeVan T.D.
Serum level of nutritional antioxidants are decreased in veteran smokers with COPD
Journal of Military and Veterans' Health

Rheumatology and Immunology

Mikuls T.R., Duryee M.J., Rahman R., Anderson D.R., Sayles H.R., Hollins A., Michaud K., Wolfe F., Thiele G.E., Sokolove J., Robinson W.H., Lingampalli N., Nicholas A.P., Talmon G.A., Su K., Zimmerman M.C., Klassen L.W., Thiele G.M.
Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint
Rheumatology (Oxford, England)

Bryant R. England; Ted R. Mikuls; Fenglong Xie; Shuo Yang; Lang Chen; Jeffrey R. Curtis
Herpes Zoster as a Risk Factor for Incident Giant Cell Arteritis
Arthritis and Rheumatology

Peper S.M., Lew R., Mikuls T., Brophy M., Rybin D., Wu H., O'Dell J.
Rheumatoid Arthritis Treatment After Methotrexate: The Durability of Triple Therapy Versus Etanercept
Arthritis Care and Research