Faculty Publications

Department of Internal Medicine faculty publish in a wide variety of journals and on topics pertaining to all our divisions. Special thanks to all faculty, house officers, postdoctoral fellows, students, and staff who perform and support the research mission of the department. We also thank those who serve on the Internal Medicine Research Council (IMRC) for their research advocacy and research training efforts. We obtained the data for this report from ADIS and Scopus. Please contact us if you have questions.


Notable Publications - 1st and 2nd Quarter 2018

Cardiovascular Medicine
Gastroenterology and Hepatology
General Medicine
Infectious Diseases
Oncology and Hematology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology and Immunology

Cardiovascular Medicine

Lundgren S., Poon C.Y.M., Selim A., Lowes B.D., Zolty R., Burdorf A., Potashnik-Peled Y., Moulton M.J., Um J.Y., Raichlin E., Depression and anxiety in patients undergoing left ventricular assist device implantation, International Journal of Artificial Organs

acta.JPGKuss M., Kim J., Qi D., Wu S., Lei Y., Chung S., Duan B., Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function, Acta Biomaterialia,

*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 1st and 2nd Quarter 2018

Schleifer J.W., Pislaru S.V., Lin G., Powell B.D., Espinosa R., Koestler C., Thome T., Polk L., Li Z., Asirvatham S.J., Cha Y.-M., Effect of ventricular pacing lead position on tricuspid regurgitation: A randomized prospective trial, Heart Rhythm

Schleifer J.W., Manocha K.K., Asirvatham S.J., Noseworthy P.A., Gulati R., Friedman P.A., Madhavan M., Munger T.M., Cooper L.T., Reeder G.S., Holmes D.R., Jr., Kapa S., Feasibility of Performing Radiofrequency Catheter Ablation and Endomyocardial Biopsy in the Same Setting, American Journal of Cardiology

Abdulsalam N., Goldsweig A.M., Porous CardiovascularFORM Septal Occluder Balloons Within the Right Atrial Cavity, JACC: Cardiovascularvascular Interventions

Aggarwal S., Xie F., High R., Pavlides G., Porter T.R., Prevalence and Predictive Value of Microvascular Flow Abnormalities after Successful Contemporary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction, Journal of the American Society of Echocardiography


Gastroenterology and Hepatology

Murali Ganesan; Raghubendra Singh Dagur; Edward Makarov; Larisa I. Poluektova; Srivatsan Kidambi; Natalia A. Osna, Matrix stiffness regulate apoptotic cell death in HIV-HCV co-infected hepatocytes, Biochemical and Biophysical Research Communications


General Medicine

Campbell W.S., Karlsson D., Vreeman D.J., Lazenby A.J., Talmon G.A., Campbell J.R., A computable pathology report for precision medicine: Extending an observables ontology unifying SNOMED CT and LOINC, Journal of the American Medical Informatics Association

Derrick Antoniak; Chandrakanth Are; Chad Vokoun; Kaeli Samson; Lynette Smith; Jason Shiffermiller, The Relationship Between Age and Chronic Kidney Disease in Patients Undergoing Pancreatic Resection, Journal of Gastrointestinal Surgery,


Infectious Diseases

Kalil A.C., Gilbert D.N., Winslow D.L., Masur H., Klompas M., Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines, Clinical Infectious Diseases


Oncology and Hematology

Gale R.P., Armitage J.O., Are we prepared for nuclear terrorism?, New England Journal of Medicine

Teply B.A., Wang H., Luber B., Sullivan R., Rifkind I., Bruns A., Spitz A., DeCarli M., Sinibaldi V., Pratz C.F., Lu C., Silberstein J.L., Luo J., Schweizer M.T., Drake C.G., Carducci M.A., Paller C.J., Antonarakis E.S., Eisenberger M.A., Denmeade S.R., Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study, The Lancet Oncology

Holstein S.A., Avet-Loiseau H., Hahn T., Ho C.M., Lohr J.G., Munshi N.C., Paiva B., Pasquini M.C., Tario J.D., Usmani S.Z., Wallace P.K., Weisel K., McCarthy P.L., BMT CTN Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling: Summary and Recommendations from the Organizing Committee, Biology of Blood and Marrow Transplantation

Haney S.L., Chhonker Y.S., Varney M.L., Talmon G., Murry D.J., Holstein S.A., Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor, Investigational New Drugs

Publication of the Quarter 2nd Quarter 2018Bhatt V.R., Chen B., Gyawali B., Lee S.J., Socioeconomic and health system factors associated with lower utilization of hematopoietic cell transplantation in older patients with acute myeloid leukemia, Bone Marrow Transplantation

* Selected as the UNMC Department of Internal Medicine Publication of the Quarter - 1st and 2nd Quarter 2018


Pulmonary, Critical Care, Sleep and Allergy

Tara M. Nordgren; Kristina L. Bailey; Art J. Heires; Dawn Katafiasz; Debra J. Romberger, Effects of agricultural organic dusts on human lung-resident mesenchymal stem (Stromal) cell function, Toxicological Sciences

 Sinha R., Weissenburger-Moser L.A., Clarke J.L., Smith L.M., Heires A.J., Romberger D.J., LeVan T.D., Short term dynamics of the sputum microbiome among COPD patients, PLoS ONE


Rheumatology and Immunology

Bryant R. England; Joshua F. Baker; Harlan Sayles; Kaleb Michaud; Liron Caplan; Lisa A. Davis; Grant W. Cannon; Brian C. Sauer; E. Blair Solow; Andreas M. Reimold; Gail S. Kerr; Ted R. Mikuls, Body Mass Index, Weight Loss, and Cause-Specific Mortality in Rheumatoid Arthritis, Arthritis Care and Research

physiology.JPGDuryee M.J., Wiese B.M., Bowman J.R., Vanlandingham J.D., Klassen L.W., Thiele G.E., Hunter C.D., Anderson D.R., Mikuls T.R., Thiele G.M., Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation, American Journal of Physiology - Gastrointestinal and Liver Physiology,

*Selected as a UNMC Department of Internal Medicine Honorable Mention Publication – 1st and 2nd Quarter 2018

Khadge S., Thiele G.M., Sharp J.G., McGuire T.R., Klassen L.W., Black P.N., DiRusso C.C., Talmadge J.E., Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation, Journal of Mammary Gland Biology and Neoplasia

Mikuls T.R., Duryee M.J., England B.R., Anderson D.R., Hearth-Holmes M., Su K., Michaud K., Payne J.B., Sayles H., Hunter C., McGowan J.D., Klassen L.W., Thiele G.M., Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions, International Immunopharmacology

Gulsen Ozen; Diane L. Kamen; Ted R. Mikuls; Bryant R. England; Frederick Wolfe; Kaleb Michaud, Trends and Determinants of Osteoporosis Treatment and Screening in Patients With Rheumatoid Arthritis Compared to Osteoarthritis, Arthritis Care and Research

Notable Publications of the Quarter - 4th Quarter 2017  

Notable Publications - 4th Quarter 2017

Cardiovascular Medicine
Diabetes, Endocrine & Metabolism
Gastroenterology and Hepatology
Infectious Diseases
Oncology and Hematology
Pulmonary, Critical Care, Sleep and Allergy
Rheumatology and Immunology

Cardiovascular Medicine

Chatzizisis Y.S., Toutouzas K., Giannopoulos A.A., Riga M., Antoniadis A.P., Fujinom Y., Mitsouras D., Koutkias V.G., Cheimariotis G., Doulaverakis C., Tsampoulatidis I., Chouvarda I., Kompatsiaris I., Nakamura S., Rybicki F.J., Maglaveras N., Tousoulis D., Giannoglou G.D.
Association of global and local low endothelial shear stress with high-risk plaque using intracoronary 3D optical coherence tomography: Introduction of 'shear stress score
European Heart Journal Cardiovascular Imaging

Wu S., Peng H., Li X., Streubel P.N., Liu Y., Duan B.
Effect of scaffold morphology and cell co-culture on tenogenic differentiation of HADMSC on centrifugal melt electrospun poly (L-lactic acid) fibrous meshes 

4thPuboftheQuarterWu S., Wang Y., Streubel P.N., Duan B.
Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation
Acta Biomaterialia

*Selected as the UNMC Department of Internal Medicine Publication of the Quarter – 4 th Quarter 2017 

Aggarwal S, Xie F, Porter TR
Masking and Unmasking of Isolated Noncompaction of the Left Ventricle With Real-Time Contrast Echocardiography
Circ Cardiovasc Imaging

Kuss M.A., Wu S., Wang Y., Untrauer J.B., Li W., Lim J.Y., Duan B.
Prevascularization of 3D printed bone scaffolds by bioactive hydrogels and cell co-culture
Journal of Biomedical Materials Research - Part B Applied Biomaterials

Goldsweig A.M., Kennedy K.F., Kolte D., Abbott J.D., Gordon P.C., Sharaf B.L., Sellke F.W., Ehsan A., Sodha N.R., Rutar F., Aronow H.D.
Predictors of patient radiation exposure during transcatheter aortic valve replacement
Catheterization and Cardiovascular Interventions 


Diabetes, Endocrine & Metabolism

Gopalakrishnan Natarajan; Curtis Perriotte-Olson; Fatema Bhinderwala; Robert Powers; Cyrus V. Desouza; Geoffrey A. Talmon; Jiang Yuhang; Matthew C. Zimmerman; Alexander V. Kabanov; Viswanathan Saraswathi
Nanoformulated copper/zinc superoxide dismutase exerts differential effects on glucose vs lipid homeostasis depending on the diet composition possibly via altered AMPK signaling
Translational Research 


Gastroenterology and Hepatology

HonPubof4thQuarterBurchett K.M., Etekpo A., Batra S.K., Yan Y., Ouellette M.M.
Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells

*Selected as the UNMC Department of Internal Medicine Honorable Mention Publication – 4 th Quarter 2017


Infectious Diseases

Jones R.L., Sayles H.R., Fey P.D., Rupp M.E.
Effect of Clinical Variables on the Volume of Blood Collected for Blood Cultures in an Adult Patient Population
Infection Control and Hospital Epidemiology 


Oncology and Hematology

Michael Baine; Tim Dorius; Nathan Bennion; Morshed Alam; Lynette Smith; Weining Zhen; Apar Ganti
Chemoradiotherapy for locally advanced squamous cell carcinoma of the oropharynx
Oral Oncology 

Haney S.L., Allen C., Varney M.L., Dykstra K.M., Falcone E.R., Colligan S.H., Hu Q., Aldridge A.M., Wright D.L., Wiemer A.J., Holstein S.A.
Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells

Baine M.J., Dorius T., Bennion N., Smith L., Zhen W., Ganti A.K.
Weight loss and percutaneous endoscopic gastrostomy tube placement during chemoradiotherapy for locally advanced cancer of the oropharynx do not negatively impact outcomes
Frontiers in Oncology


Pulmonary, Critical Care, Sleep and Allergy

Poole J.A., Mikuls T.R., Duryee M.J., Warren K.J., Wyatt T.A., Nelson A.J., Romberger D.J., West W.W., Thiele G.M.
A role for B cells in organic dust induced lung inflammation
Respiratory Research

Sapkota M., Burnham E.L., DeVasure J.M., Sweeter J.M., Hunter C.D., Duryee M.J., Klassen L.W., Kharbanda K.K., Sisson J.H., Thiele G.M., Wyatt T.A.
Malondialdehyde–Acetaldehyde (MAA) Protein Adducts Are Found Exclusively in the Lungs of Smokers with Alcohol Use Disorders and Are Associated with Systemic Anti-MAA Antibodies
Alcoholism: Clinical and Experimental Research

Hanson C., Lyden E., Weissenburger-Moser L., Furtado J., Romberger D.J., LeVan T.D.
Serum level of nutritional antioxidants are decreased in veteran smokers with COPD
Journal of Military and Veterans' Health


Rheumatology and Immunology

Mikuls T.R., Duryee M.J., Rahman R., Anderson D.R., Sayles H.R., Hollins A., Michaud K., Wolfe F., Thiele G.E., Sokolove J., Robinson W.H., Lingampalli N., Nicholas A.P., Talmon G.A., Su K., Zimmerman M.C., Klassen L.W., Thiele G.M.
Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint
Rheumatology (Oxford, England)

Bryant R. England; Ted R. Mikuls; Fenglong Xie; Shuo Yang; Lang Chen; Jeffrey R. Curtis
Herpes Zoster as a Risk Factor for Incident Giant Cell Arteritis
Arthritis and Rheumatology

Peper S.M., Lew R., Mikuls T., Brophy M., Rybin D., Wu H., O'Dell J.
Rheumatoid Arthritis Treatment After Methotrexate: The Durability of Triple Therapy Versus Etanercept
Arthritis Care and Research