UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Bioinformatics & Systems Biology Faculty

Faculty Departments

  • Anesthesiology
  • Biochemistry and Molecular Biology
  • Biology (UNO)
  • Cellular and Integrative Physiology
  • College of Pharmacy
  • Computer Science (UNO)
  • Eppley Cancer Institute
  • Genetics Cell Biology and Anatomy
  • Information Science and Technology (UNO)
  • Interdisciplinary Informatics (UNO)
  • Internal Medicine - DEM
  • Mathematics (UNO)
  • Munroe-Meyer Institute
  • Neurological Sciences
  • Obstetrics and Gynecology
  • Pathology and Microbiology
  • Pharmacology and Experimental Neuroscience
  • Pharmacy Practice and Science
  • Surgery

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Faculty

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Maher Y. Abdalla, PhD
Assistant Professor, Department of Pathology and Microbiology

Research focus: Reactive Oxygen Species (ROS), Heme Oxygenase-1 (HO-1) and immune cells in pancreatic ductal adenocarcinoma (PDAC) and prostate cancer.

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Hesham Ali, PhD
Dean, Department of Information Science and Technology (UNO)

Research focus: Developing secure and energy-aware wireless infrastructure to address tracking and monitoring problems in medical environments, particularly to study mobility profiling for various groups and to conduct a population analysis approach to advancing healthcare research.

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Hamid Band

Hamid Band, MD, PhD
Professor, Eppley Cancer Institute

Research focus: Regulation of receptor signaling by endocytic traffic; Cbl-family and CHIP ubiquitin ligases; EHD-family endocytic recycling regulators; mouse genetic models; cancer and stem cell biology.

Vimla Band

Vimla Band, PhD
Professor and Chair, Department of Genetics, Cell Biology and Anatomy

Research focus: Delineate molecular mechanisms of early steps in transformation of mammary epithelial cells with the goal of identifying novel molecular diagnostic/prognostic markers and potential therapy targets of breast cancers.

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Kiran Bastola, PhD
Professor, Department of Information Science and Technology (UNO)

Research focus: Computational biology including gene regulation with noncoding RDA, mining for interesting patterns form genomic sequences for use in molecular diagnostics, public health, secondary metabolism and biology of the mitochondria in disease, as well as extreme environments.

Ken Bayles

Kenneth W. Bayles, PhD
Professor, Department of Pathology and Microbiology

Research focus: Staphylococcus aureus infections; biofilm development; the control of bacterial programmed cell death.

Kishor Bhakat

Kishor K. Bhakat, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Mitotic gene bookmarking - A novel dimension of epigenetic memory in cancer for post-mitotic transcriptional reactivation; APE1 and its acetylation - A potential prognostic and predictive biomarker in cancer.

Jennifer Black

Jennifer Black, PhD
Professor, Eppley Cancer Institute

Research focus: Colon cancer; endometrial cancer; pancreatic cancer; cell signaling (kinases and phosphatases) cell cycle regulation; control of protein translation in cancer; protein kinase C; PP2A.

Keely Buesing

Keely Buesing, MD, FACS
Associate Professor, Department of Surgery

Research focus: Large animal and pulmonary cellular investigation of novel therapeutics targeting Acute Respiratory Distress Syndrome (ARDS).

Siddappa Byrareddy

Siddappa Byrareddy, PhD
Professor, Department of Pharmacology & Experimental Neuroscience

Research focus: Understanding host-virus dynamics using molecular biology, virology, immunology, systems biology, and genomic tools to develop prevention strategies for HIV/AIDS and other infectious diseases, such as Zika virus.

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Scott Campbell

W. Scott Campbell, MBA, PhD
Associate Professor, Department of Pathology and Microbiology

Research focus: Health informatics and pathology informatics.

Kishore Challagundla

Kishore Challagundla, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Role of extra cellular vesicles (EV's) and the non-coding RNAs in affecting immunotherapy response and escaping immune surveillance in pediatric cancers, in particular neuroblastoma and acute myeloid leukemia.

Pi-Wan Cheng

Pi-Wan Cheng, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Development of glycan-based strategies to treat malignant cancer as well as prevent and treat infections.

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Parvathi Chundi, PhD
Professor, Department of Computer Science (UNO)

Research focus: Machine learning algorithms for unstructured data collections; serious games; Big Data Frameworks.

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Kate Cooper (Dempsey), PhD
Assistant Professor, College of Information Science & Technology (UNO)

Research focus: Microbiome analysis related to diet and consumer/patient health; bioinformatics education.

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John Davis

John S. Davis, PhD
Professor, Director of Research and Development - Olson Center for Women's Health, Department of Obstetrics and Gynecology

Research focus: Reproductive endocrinology and oncology.

Paul Davis

Paul Davis, PhD
Professor, Department of Biology (UNO)

Research focus: Investigating and developing novel approaches to prevent and treat human parasitic infections, using approaches that include molecular biology, bioinformatics, -omics, high-content imaging, and genetics.

Andrew Dudley

Andrew Dudley, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine.

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Howard Fox

Howard S. Fox, MD, PhD
Professor, Department of Neurological Sciences

Research focus: Neurodegeneration, brain dysfunction and viral infections of the brain.

Ann Fruhling, PhD

Ann Fruhling, PhD
Professor, College of Information Science and Technology (UNO)

Research focus: User interface design and evaluation; usability studies; information systems design strategies for medical emergency response systems, e-health applications; health informatics; agile system development; implementation and management strategies.

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Lie Gao

Lie Gao, MD, PhD
Assistant Professor, Department of Cellular and Integrative Physiology

Research focus: Role of skeletal muscle Nrf2 in exercise-induced cardioprotection, with a focus of extracellular vesicle-mediated cell-to-cell antioxidant communication, by employing skeletal muscle-specific transgenic mouse lines.

Howard Gendelman

Howard E. Gendelman, MD
Professor, Department of Pharmacology and Experimental Neuroscience

Research focus: Development and testing of HIV-1 cure strategies; Basic and clinical studies on novel medicines to treat Parkinson's disease.

Dario Ghersi, PhD

Dario Ghersi, PhD
Associate Professor, College of Information Science and Technology (UNO)

Research focus: Large-scale cancer genomics datasets, integrating different types of data (including protein structure) to gain insight into the molecular bases of cancer and immune system function.

Gargi Ghosal

Gargi Ghosal, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Understand the basic science underlying replication stress response in cancer and aging; identify new targets and bio-markers for cancer therapies and facilitate the development of strategies to overcome drug resistance and improve cancer therapies.

Stacey Gilk

Stacey Gilk, PhD
Assistant Professor, Department of Pathology and Microbiology

Research focus: Microbial pathogenesis; Coxiella, Rickettsia

Karen Gould

Karen Gould, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Estrogen receptor alpha regulation of B cell receptor signaling, B cell fate, and lupus pathogenesis.

Babu Guda

Chittibabu (Babu) Guda, PhD
Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Development and application of computational methods for genomic data analyses including cancer genomics, functional annotation of proteins, pathways, networks and systems in biomedical research.

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Kyle Hewitt, PhD

Kyle Hewitt, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy

Research focus: Hematopoitic stem and progenitor cell control of blood production during development and/or regeneration following disease or injury; transcriptional and epigentic mechanisms that cause hematologic disorders; tissue and cellular heterogeneity; CRISPR/Cas9-mediated disruption of gene regulatory networks and cell signaling mechanisms.

Tony Hollingsworth

Michael A. (Tony) Hollingsworth, PhD
Professor, Eppley Cancer Institute

Research focus: Basic and translational research in pancreatic cancer, including investigation of the biology of tumor progression, discovery and validation of biomarkers of early detection and disease progression, development and testing of novel therapeutics, including targeted therapies and immunotherapies.

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Adam Karpf

Adam R. Karpf, PhD
Professor, Eppley Cancer Institute

Research focus: Ovarian cancer biology and therapeutics; Cancer epigenetics.

Tammy Kielian

Tammy L. Kielian, PhD
Professor, Department of Pathology and Microbiology

Research focus: Host-pathogen interactions, immunology, neuroimmunology, translational therapeutics.

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Marilynn Larson

Marilynn Larson, PhD
Assistant Professor, Department of Pathology and Microbiology

Research focus: Host and intracellular pathogen interactions, and determining the mechanisms that allow the Tier 1 select agent Francisella tularensis to persist and rapidly replicate within infected macrophages.

Ming-Fong Lin

Ming-Fong Lin, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Mechanism of cell growth regulation by steroids via cross-talk of ROS and tyrosine phosphorylation signaling.

Guoqing Lu, PhD

Guoqing Lu, PhD
Professor, Department of Biology & Interdisciplinary Informatics (UNO)

Research focus: Theoretical and applied bioinformatics, with a focus on comparative genomics and evolutionary informatics.

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Mahbubul Majumder, PhD

Mahbubul Majumder, PhD
Associate Professor, Department of Mathematics (UNO)

Research focus: Exploratory data analysis; data visualization and visual inference; statistical modeling; data science.

Luis Marky

Luis Marky, PhD
Professor, College of Pharmacy

Research focus: Biophysical chemistry and molecular forces that control the conformational stability and flexibility of nucleic acids, including Okazaki fragments, hairpin loops, intramolecular triplexes, G-quadruplexes, C-quadruplexes, and three- & four-arm DNA junctions and their interaction with drugs.

Karoly Mirnics

Karoly Mirnics, MD, PhD
Director, Munroe-Meyer Institute

Research focus: Animal models of neurodevelopmental and psychiatric disorders; effects of Gene-Environmental-Drug interactions on the developing brain; role of disrupted cholesterol biosynthesis of brain function - all using genetic, molecular, cellular and biochemical tools in our studies, coupled with drug screening and mouse behavioral assessments.

Paras Kumar Mishra

Paras Kumar Mishra, PhD
Associate Professor, Department of Cellular and Integrative Physiology

Research focus: MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy.

DJ Murry

DJ Murry, PharmD
Professor, Department of Pharmacy Practice and Science

Research focus: Ways to individualize drug therapy using pharmacokinetic and pharmacogenomics information; from in vitro metabolism and transport studies, animal pharmacokinetic studies, to clinical studies evaluating drug therapy in patients.

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Caroline Ng

Caroline Ng, PhD
Assistant Professor, Department of Pathology & Microbiology

Research focus: Biology and pathogenesis of Plasmodium falciparum, genetic and molecular mechanisms underlying drug resistance.

 

Robert B. Norgren, PhD
Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Use of nonhuman primate genomics to better understand human genetic disease.

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Scot Ouellette

Scot Ouellette, PhD
Associate Professor, Department of Pathology & Microbiology

Research focus: Chlamydial microbiology: bacterial cell division, gene regulation, host-pathogen interactions.

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Gurudutt Pendyala

Gurudutt N. Pendyala, PhD
Associate Professor, Department of Anesthesiology

Research focus: Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNAs at the synapse in drug addiction, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics.

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Matthew Rizzino

Matthew Rizzo, MD, FAAN
Professor, Department of Neurological Sciences

Research focus: Memory disorders; behavioral consequences of aging and neurological disorders.

Jim Rogers, PHD

Jim Rogers, PhD
Associate Professor, Department of Mathematics (UNO)

Research focus: Mathematical biology.

Don Ronning

Don Ronning, PhD
Professor, Department of Pharmaceutical Sciences

Research focus: Discovery and development of anti-infective and anti-cancer compounds.

Jordan Rowley, PhD

Jordan Rowley, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy

Research focus: 3D organization of DNA within the nucleus.

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Jawed Siddiqui

Jawed Siddiqui, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Bone metastasis, bone microenvironment, chemokines and cytokines, osteoimmunology, bone-muscle cross-talk, and cancer therapeutics.

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William Tapprich, PhD
Professor, Department of Biology (UNO)

Research focus: Understanding the structure and function of viral RNA molecules, particularly enteroviral genomic RNA.

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Saraswathi Viswanathan

Saraswathi Viswanathan, PhD
Assistant Professor, Department of Internal Medicine - Diabetes, Endocrine and Metabolism

Research focus: Determine the link between obesity and cardiovascular disease.

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Hanjun Wang

Hanjun Wang, MD
Associate Professor, Department of Cellular and Integrative Physiology

Research focus: Cardiovascular reflexes during exercise; neural control mechanisms underlying the exaggerated cardiovascular response and hyperventilation during exercise in the chronic heart failure state.

David Warren

David Warren, PhD
Associate Professor, Department of Neurological Sciences

Research focus: Cognitive neuroscience investigations of cognition (especially memory) and related brain networks that combine neuroimaging, neuropsychological, and neurostimulation methods.

Nicholas Woods

Nicholas Woods, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Systems biology based analysis of cancer signaling pathways.

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Ying Yan

Ying Yan, PhD
Professor, Department of Radiation Oncology

Research focus: Tumorigenesis, cancer progression and metastasis, and development of new anticancer agents.

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