UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Molecular Genetics & Cell Biology Faculty

Faculty Departments

  • Biochemistry and Molecular Biology
  • Cellular and Integrative Physiology
  • College of Dentistry
  • College of Pharmacy
  • College of Public Health
  • Eppley Institute
  • Genetics Cell Biology and Anatomy
  • Internal Medicine
  • Munroe-Meyer Institute
  • Obstetrics and Gynecology
  • Ophthalmology and Visual Sciences
  • Pathology and Microbiology
  • Pediatrics
  • Pharmacology and Experimental Neuroscience
  • Radiation Oncology
  • Surgery

 

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Faculty

Hamid Band

Hamid Band, MD, PhD
Professor, Eppley Cancer Institute

Research focus: Regulation of receptor signaling by endocytic traffic; Cbl-family and CHIP ubiquitin ligases; EHD-family endocytic recycling regulators; mouse genetic models; cancer and stem cell biology.

Vimla Band

Vimla Band, PhD
Professor and Chair, Department of Genetics, Cell Biology and Anatomy

Research focus: Delineate molecular mechanisms of early steps in transformation of mammary epithelial cells with the goal of identifying novel molecular diagnostic/prognostic markers and potential therapy targets of breast cancers.

Robert Bennett

Robert Bennett, PhD
Professor, Department of Internal Medicine - Diabetes, Endocrinology and Metabolism (DEM)

Research focus: Antifibrotic effects of the hormone relaxin and related peptides; expression and signaling of relaxin receptors; internalization and degradation of relaxin, insulin and related hormones; the role of relaxin in adipose function.

Bessho

Tadayoshi Bessho, PhD
Associate Professor, Eppley Cancer Institute

Research focus: Molecular mechanism of DNA interstrand crosslink repair in mammalian cells.

Kishor Bhakat

Kishor K. Bhakat, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Mitotic gene bookmarking:  A novel dimension of epigenetic memory in cancer for post-mitotic transcriptional reactivation; APE1 and its acetylation: A potential prognostic and predictive biomarker in cancer.

 Chengfeng Bi

Chengfeng (Andy) Bi, PhD
Assistant Professor, Department of Internal Medicine - Oncology and Hematology

Research focus: Pathogenesis and molecular mechanism of hematological malignancies.

Jennifer Black

Jennifer Black, PhD
Professor, Eppley Cancer Institute

Research focus: Colon cancer; endometrial cancer; pancreatic cancer; cell signaling (kinases and phosphatases) cell cycle regulation; control of protein translation in cancer; protein kinase C; PP2A.

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Mark Carlson

Mark Carlson, MD, FACS
Professor, Department of Surgery

Research focus: Cancer; regenerative medicine; hemostasis; wound healing.

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Kishore Challagundla, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Role of extra cellular vesicles (EV's) and the non-coding RNAs in affecting immunotherapy and escaping immune surveillance in pediatric cancers, in particular neuroblastoma and acute myeloid leukemia.

Pi-Wan Cheng

Pi-Wan Cheng, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Development of glycan-based strategies to treat malignant cancer as well as prevent and treat infections.

Suyong Choi

Suyong Choi, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Phosphoinositide signaling pathways in cancer and immunology.

 

Leah Cook

Leah Cook, PhD
Assistant Professor, Department of Pathology and Microbiology

Research focus: Investigation of immune interactions within the tumor bone microenvironment that contribute to bone metastatic prostate cancer; identifying novel immunotherapeutic targets for treating and curing metastatic cancers.

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Kaustabh Datta

Kaustubh Datta, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Molecular mechanisms of cancer progression and metastasis.

Rebecca Deegan, PhD

Rebecca Deegan, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Role of free radicals signaling to transform fibroblasts and inflammatory cells in normal tissue, which results in damage to these tissues; understanding the mechanisms by which ROS promote radiation induced fibrosis and prostate cancer progression.

Punita Dhawan

Punita Dhawan, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Development of novel therapeutic targets for Gastrointestinal Cancer progression and chemoresistance; Role of signaling pathways and cancer stem cells involved in this process using cell culture, mouse and organoid models.

Bin Duan

Bin Duan, PhD
Associate Professor, Department of Internal Medicine - Cardiology

Research focus: Integrate novel biomaterials, advanced biofabrication of tissue engineering to create multi-scale complexity within engineered tissue to understand the fundamentals of cell-material interactions and mimic the native tissue for tissue regeneration.

Andrew Dudley

Andrew Dudley, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine.

Anna Dunaevsky

Anna Dunaevsky, PhD
Professor, Department of Neurological Sciences

Research focus: Synaptic plasticity and neuron-glia interactions in neurocognitive disorders.

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Jim Eudy

James Eudy, PhD
Associate Professor, Director of UNMC DNA Microarray and Sequencing Core Facility, Department of Genetics, Cell Biology and Anatomy

Research focus: Next Generation DNA Sequencing strategies for rare Mendelian disease gene identification and functional genomic technologies; biomedical interest in cancer, cardiovascular disease and virology.

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Gargi Ghosal

Gargi Ghosal, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Understand the basic science underlying replication stress response in cancer and aging, identify new targets and bio-markers for cancer therapy and facilitate the development of strategies to overcome drug resistance and improve cancer therapies.

Karen Gould

Karen Gould, PhD
Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Estrogen receptor alpha regulation of B cell receptor signaling, B cell fate, and lupus pathogenesis.

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Kyle Hewitt, PhD

Kyle Hewitt, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy

Research focus: Hematopoitic stem and progenitor cell control of blood production during development and/or regeneration following disease or injury; transcriptional and epigentic mechanisms that cause hematologic disorders; tissue and cellular heterogeneity; CRISPR/Cas9-mediated disruption of gene regulatory networks and cell signaling mechanisms.

Steve Hinrichs

Steven H. Hinrichs, MD
Chair and Professor, Department of Pathology and Microbiology

Research focus: Molecular pathogenesis and diagnostics of infectious organism, antimicrobial drug discovery and bioterrorism preparedness information technology.

Tony Hollingsworth

Michael A. (Tony) Hollingsworth, PhD
Professor, Eppley Cancer Institute

Research focus: Basic and translational research in pancreatic cancer, including investigation of the biology of tumor progress, discovery and validation of biomarkers of early detection and disease progression, development and testing of novel therapeutics, including targeted therapies and immunotherapies.

Kate Hyde

R. Katherine (Kate) Hyde, PhD
Associate Professor, Department of Biochemistry and Molecular Biology

Research focus: Understand the mechanisms that regulate leukemia development; develop treatments for hematological malignancies.

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Maneesh Jain

Maneesh Jain, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Development of genetically engineered antibody fragments for improved radioimmunotherapy for solid tumors; development of serum assays for the early diagnosis of lethal pancreatic cancer.

Keith Johnson

Keith R. Johnson, PhD
Professor, Eppley Cancer Institute

Research focus: The role the cell adhesion molecules (cadherins) play in metastasis.

Shantaram Joshi

Shantaram S. Joshi, PhD
Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Improve therapy for human B lymphocytic malignancies and pediatric cancers by means of translational research involving molecular characterization of progressive/therapy resistant malignant cells.

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Georgette Kanmogne

Georgette D. Kanmogne, PhD, MPH
Professor, Department of Pharmacology and Experimental Neuroscience

Research focus: HIV/AIDS, vascular biology and cell signaling.

Adam Karpf

Adam R. Karpf, PhD
Professor, Eppley Cancer Institute

Research focus: Ovarian cancer biology and therapeutics; Cancer epigenetics.

Kusum Kharbanda

Kusum Kharbanda, PhD
Professor, Department of Internal Medicine - Gastroenterology and Hepatology

Research focus: Alcohol liver injury with emphasis on alcohol's deleterious effect in altering the methionine metabolic pathway and lowering the ratio of the methyl donor, SAM, to its product, SAH.

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So-Youn Kim, PhD
Assistant Professor, Department of Obstetrics and Gynecology

Research focus: Oncofertility, cachexia, ovarian cancer.

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Brian Lowes

Brian Lowes, MD, PhD
Professor, Department of Internal Medicine - Cardiology

Research focus: Novel education clinical trainees and education program with a goal to develop clinicians and scientists in sub-Saharan Africa.

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Luis Marky

Luis Marky, PhD
Professor, College of Pharmacy

Research focus: Biophysical chemistry and molecular forces that control the conformational stability and flexibility of nucleic acids, including Okazaki fragments, hairpin loops, intramolecular triplexes, G-quadruplexes, C-quadruplexes, and three- & four-arm DNA junctions and their interaction with drugs.

Paras Kumar Mishra

Paras Kumar Mishra, PhD
Associate Professor, Department of Cellular and Integrative Physiology

Research focus: MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy.

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Amar Natarajan

Amarnath (Amar) Natarajan, PhD
Professor, Eppley Cancer Institute

Research focus: Developing novel target and mechanism specific therapeutics.

Ali Nawshad

Ali Nawshad, PhD
Professor, College of Dentistry

Research focus: Transforming Growth Factor (TGF) ß signaling during palate development; mechanisms of Epithelial-Mesenchymal Transition (EMT) by TGFß in HNSCC; role of TGFß signaling during dentinogenesis.

Caroline Ng

Caroline Ng, PhD
Assistant Professor, Department of Pathology & Microbiology

Research focus: Biology and pathogenesis of Plasmodium falciparum, genetic and molecular mechanisms underlying drug resistance.

 

Robert B. Norgren, PhD
Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Use of nonhuman primate genomics to better understand human genetic disease.

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Ann Olney

Ann Haskins Olney, MD
Professor, Munroe-Meyer Institute

Research focus: Dysmorphology; molecular etiology of multiple congenital anomaly syndromes; overgrowth syndromes; syndrome delineation.

Michael Ouellette

Michael M. Ouellette, PhD
Professor, Department of Internal Medicine - Gastroenterology and Hepatology

Research focus: Molecular mechanisms that determine the lifespan of human cells, including telomeres and telomerase.  Role of the small GTPases K-Ras and Rac1 in the development of pancreatic cancer and its response to conventional therapies.

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Youri Pavlov

Youri Pavlov, PhD
Professor, Eppley Cancer Institute

Research focus: Cellular systems of mutagenesis and antimutagenesis.

Gurudutt Pendyala, phD

Gurudutt N. Pendyala, PhD
Associate Professor, Department of Anesthesiology

Research focus: Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNA's at the synapse in drug addiction, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics.

Aimin Peng

Aimin Peng, PhD
Professor, College of Dentistry

Research focus: Cell cycle regulation and the DNA damage response (DDR); cellular recover process from DNA damage; protein phosphatase-dependent cell cycle and DDR regulation and its implication for cancer progression and therapy.

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Sutapa Ray

Sutapa Ray, PhD
Assistant Professor, Department of Pediatrics

Research focus: Molecular mechanisms of pediatric brain and central nervous system tumors initiation, maintenance, progression and drug resistance.

William Rizzo

William Rizzo, MD
Professor, Department of Pediatrics

Research focus: Sjogren-Larsson Syndrome and other inherited metabolic diseases.

Kerry Rodabaugh

Kerry Rodabaugh, MD
Professor, Department of Obstetrics and Gynecology

Research focus: Gynecologic oncology.

Don Ronning, PhD

Don Ronning, PhD
Professor, Department of Pharmaceutical Sciences

Research focus: Discovery and development of anti-infective and anti-cancer compounds.

Jordan Rowley, Phd

Jordan Rowley, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy

Research focus: 3D organization of DNA within the nucleus.

Shyamal Roy

Shyamal K. Roy, PhD
Professor, Department of Obstetrics & Gynecology and Cellular & Integrative Physiology

Research focus: Endocrine regulation of follicular development, growth factors, signal transduction in ovarian cells and biochemistry of granulosa cells.

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Micah Schott

Micah Schott, PhD
Assistant Professor, Department of Biochemistry & Molecular Biology

Research focus: Cell biology of lipids in metabolic disease.

Polina Shcherbakova

Polina Shcherbakova, PhD
Professor, Eppley Cancer Institute

Research focus: Mechanisms controlling genome stability in eukaryotic cells, particularly the functions of DNA polymerases, DNA replication fidelity and the relationship between DNA polymerase defects and cancer.

Jawed Siddiqui

Jawed Siddiqui, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Bone metastasis, bone microenvironment, chemokines and cytokines, osteoimmunology, bone-muscle cross-talk, and cancer therapeutics.

Paul Sorgen

Paul Sorgen, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Advancing our understanding of the fundamental mechanisms of gap junction regulation in the heart, with particular interest and expertise in protein-protein interactions mediated by the carboxylterminal domain of connexins.

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Tahir Tahirov

Tahir Tahirov, PhD
Professor, Eppley Cancer Institute

Research focus: Reveal the structure basis of the mechanisms covering the key stages in the expression and duplication/repair of genes and to learn how the disease-related mutations in proteins disrupt these key processes.

Wallace Thoreson

Wallace B. Thoreson, PhD
Professor, Department of Ophthalmology and Visual Sciences

Research focus: Visual information processing by the retina; electrophysiology and optical imaging techniques to study transmission at ribbon synapses of rod and cone photoreceptors.

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James Wahl

James Wahl, PhD
Professor, College of Dentistry

Research focus: Understand the role of desmosomes play in maintaining the normal phenotype of squamous epithelial tissues and to determine if their alteration during tumorigenesis influences cell motility, metastasis and signaling.

Hanjun Wang, PhD

Hanjun Wang, MD
Associate Professor, College of Cellular and Integrative Physiology

Research focus: Cardiovascular reflexes during exercise; neural control mechanisms underlying the exaggerated cardiovascular response and hyperventilation during exercise in the chronic heart failure state.

Nicholas Woods

Nicholas Woods, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Systems biology based analysis of cancer signaling pathways.

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Jingwei Xie

Jingwei Xie, PhD
Professor, Department of Surgery-Transplant

Research focus: Synthesis, surface modification, self-assembly of materials at nanometer scale to address problems in the field of tissue engineering, regenerative medicine and drug/gene delivery.

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Ying Yan

Ying Yan, PhD
Professor, Department of Radiation Oncology

Research focus: Tumorigenesis, cancer progression and metastasis, and development of new anticancer agents.

Sowmya Yelamanchili, PhD

Sowmya Yelamanchili, PhD
Assistant Professor, Department of Anesthesiology

Research focus: MicroRNAs in neurodegenerative diseases, HIV, Parkinson's Disease.

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